CAS: 193275-84-2 - LONAFARNIB

Formula: C₂₇H₃₁Br₂ClN₄O₂

InChI: InChI=1S/C27H31Br2ClN4O2/c28-20-12-19-2-1-18-13-21(30)14-22(29)24(18)25(26(19)32-15-20)17-5-9-33(10-6-17)23(35)11-16-3-7-34(8-4-16)27(31)36/h12-17,25H,1-11H2,(H2,31,36)/t25-/m1/s1

InChI key: InChIKey=DHMTURDWPRKSOA-RUZDIDTESA-N

SMILES: O=C(N)N1CCC(CC(=O)N2CCC(CC2)C3C4=NC=C(Br)C=C4CCC=5C=C(Cl)C=C(Br)C53)CC1

Synonyms:

• ( )4-(2-(4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H-benzo(5,6)cyclohepta (1,2-b)pyridin-11-yl)-1-piperidinyl)-2-oxoethyl)-1-piperidinecarboxami de
• 1-Piperidinecarboxamide, 4-[2-[4-[(11R)-3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-
• 4-[2-[4-[(11R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide
• Sarasar
• Sch 66336
• Zokinvy

LONAFARNIB

CAS: 193275-84-2

• Formula: C₂₇H₃₁Br₂ClN₄O₂
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 638.8216

Lonafarnib

CAS: 193275-84-2

• Formula: C₂₇H₃₁Br₂ClN₄O₂
• Color and Shape: Off-White Solid
• Molecular weight: 638.83

Lonafarnib-d9

CAS: 193275-84-2

• Formula: C₂₇H₂₂Br₂ClN₄O₂D₉
• Molecular weight: 647.89

Lonafarnib

CAS: 193275-84-2

Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 …

• Formula: C₂₇H₃₁Br₂ClN₄O₂
• Purity: 98% - 99.04%
• Color and Shape: Solid
• Molecular weight: 638.82

Lonafarnib

CAS: 193275-84-2

Applications Lonafarnib is an orally bioavailable tricyclic inhibitor of farnesyl protein transferase. It inhibits Rheb …

• Formula: C₂₇H₃₁Br₂ClN₄O₂
• Color and Shape: Neat
• Molecular weight: 638.82

Lonafarnib

CAS: 193275-84-2

Lonafarnib is a selective, non-peptidomimetic competitive inhibitor of farnesyl trasferase with IC50 of 1.9nM. Farneslyl …

• Formula: C₂₇H₃₁Br₂ClN₄O₂
• Purity: Min. 95%
• Molecular weight: 638.82 g/mol

Lonafarnib-d9

CAS: 193275-84-2

• Formula: C₂₇D₉H₂₂Br₂ClN₄O₂
• Color and Shape: Neat
• Molecular weight: 647.877