Ras
Ras proteins are small GTPases that act as molecular switches in the MAPK signaling pathway, controlling cell growth, differentiation, and survival. Activated Ras initiates a signaling cascade that includes Raf, MEK, and ERK, leading to various cellular responses. Mutations in Ras genes are common in cancers, making Ras an important focus of cancer research. At CymitQuimica, we offer a range of Ras modulators to support your research in cancer biology, signal transduction, and therapeutic development.
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Ketoconazole
CAS:65277-42-1
Ketoconazole (R-41400), a CYP3A4 inhibitor, is an imidazole anti-fungal agent.
Formula:
C26H28Cl2N4O4
Purity:
99.53% - 99.62%
Color and Shape:
Crystals From 4-Methylpentanone Solid
Molecular weight:
531.43
Ref: TM-T0679
| 1g | 96.00 € | ||
| 5g | 349.00 € | ||
| 50mg | 39.00 € | ||
| 100mg | 50.00 € | ||
| 200mg | 63.00 € | ||
| 500mg | 79.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
HJC0197
CAS:1383539-73-8
HJC0197 is a selective Epac antagonist; blocks cAMP-induced activation with IC50=5.9 μM for Epac2.
Formula:
C19H21N3OS
Purity:
98.05%
Color and Shape:
Solid
Molecular weight:
339.45
Ref: TM-T15485
| 2mg | 38.00 € | ||
| 5mg | 54.00 € | ||
| 10mg | 86.00 € | ||
| 25mg | 135.00 € | ||
| 50mg | 188.00 € | ||
| 100mg | 283.00 € | ||
| 200mg | 426.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
BI-3406
CAS:2230836-55-0
BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless …
Formula:
C23H25F3N4O3
Purity:
99.20% - 99.66%
Color and Shape:
Solid
Molecular weight:
462.46
Ref: TM-T12979
| 1mg | 73.00 € | ||
| 5mg | 160.00 € | ||
| 10mg | 250.00 € | ||
| 25mg | 464.00 € | ||
| 50mg | 663.00 € | ||
| 100mg | 919.00 € | ||
| 500mg | 1,833.00 € | ||
| 1mL*10mM (DMSO) | 170.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
MBQ-167
CAS:2097938-73-1
MBQ-167 is a dual inhibitor of Rac/Cdc42 (IC50s: 103 nM for Rac 1/2/3 and 78 …
Formula:
C22H18N4
Purity:
98.07% - 98.74%
Color and Shape:
Solid
Molecular weight:
338.41
Ref: TM-T16021
| 1mg | 37.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 111.00 € | ||
| 25mg | 208.00 € | ||
| 50mg | 376.00 € | ||
| 100mg | 567.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
MRTX-1257
CAS:2206736-04-9
MRTX-1257: selective, irreversible KRAS G12C inhibitor; IC50 of 900 pM; 31% bioavailable in mice; 77% …
Formula:
C33H39N7O2
Purity:
96.59% - 99.07%
Color and Shape:
Solid
Molecular weight:
565.71
Ref: TM-T16143
| 1mg | 64.00 € | ||
| 2mg | 89.00 € | ||
| 5mg | 131.00 € | ||
| 10mg | 220.00 € | ||
| 25mg | 371.00 € | ||
| 50mg | 557.00 € | ||
| 100mg | 797.00 € | ||
| 1mL*10mM (DMSO) | 170.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
ARS-1630
CAS:1698055-86-5
ARS-1630 is a mutant K-ras G12C inhibitor. It is a less active enantiomer of ARS-1620.
Formula:
C21H17ClF2N4O2
Purity:
97.81%
Color and Shape:
Solid
Molecular weight:
430.84
Ref: TM-T10376
| 1mg | 52.00 € | ||
| 5mg | 117.00 € | ||
| 10mg | 170.00 € | ||
| 25mg | 325.00 € | ||
| 50mg | 469.00 € | ||
| 100mg | 615.00 € | ||
| 1mL*10mM (DMSO) | 134.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
K-Ras G12C-IN-4
CAS:2376328-55-9
K-Ras G12C-IN-4 是一种 KRAS G12C 共价抑制剂。
Formula:
C31H33ClN4O4
Purity:
99.00%
Color and Shape:
Solid
Molecular weight:
561.07
Ref: TM-T11738
| 1mg | 74.00 € | ||
| 5mg | 170.00 € | ||
| 10mg | 250.00 € | ||
| 25mg | 424.00 € | ||
| 50mg | 562.00 € | ||
| 100mg | 827.00 € | ||
| 200mg | 1,111.00 € | ||
| 1mL*10mM (DMSO) | 202.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
PROTAC K-Ras Degrader-3
CAS:3043670-68-1
PROTAC K-Ras Degrader-3 is a PROTAC degrader targeting K-Ras, exhibiting a DC50 value of ≤ …
Formula:
C57H67F2N9O6
Color and Shape:
Solid
Molecular weight:
1012.20
Ref: TM-T200521
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 27 May 2025
KRAS inhibitor-33
KRAS inhibitor-33 (compound 115a) is a pyrido[2,3-d]pyrimidine derivative that serves as an effective inhibitor of …
Formula:
C33H39ClF2N6O3
Color and Shape:
Solid
Molecular weight:
641.15
Ref: TM-T201044
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 27 May 2025
MRTF-A-IN-1
MRTF-A-IN-1 (compound 14) is an inhibitor of MRTF-A. It effectively suppresses cell proliferation and induces …
Formula:
C22H21N3
Color and Shape:
Solid
Molecular weight:
327.42
Ref: TM-T201311
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 27 May 2025
BI1701963
BI1701963 is an orally effective inhibitor that targets the SOS1 and KRAS interaction, specifically inhibiting …
Formula:
C47H62N8O4S
Color and Shape:
Solid
Molecular weight:
835.11
Ref: TM-T201333
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 27 May 2025
MRTF-A-IN-2
MRTF-A-IN-2 (compound 16) is an inhibitor of MRTF-A. It effectively suppresses cell proliferation and induces …
Color and Shape:
Odour Solid
Ref: TM-T200620
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 27 May 2025
KRAS G12C inhibitor 60
KRAS G12C Inhibitor 60 (compound 23), a selective inhibitor targeting the Kras-G12C mutation, is utilized …
Formula:
C31H30F5N7O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
627.61
Ref: TM-T79166
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 27 May 2025
Pan-RAS-IN-7
CAS:2642135-72-4
Pan-RAS-IN-7 (Compound D101) is a broad-spectrum RAS inhibitor used in the synthesis of antibody-drug conjugates …
Formula:
C59H76N8O8
Color and Shape:
Solid
Molecular weight:
1025.28
Ref: TM-T201152
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 27 May 2025
KRAS inhibitor-38
CAS:3059496-10-2
KRAS Inhibitor-38 (Example 18) is a potent inhibitor capable of effectively suppressing the activity of …
Formula:
C53H68ClF2N9O8S
Color and Shape:
Solid
Molecular weight:
1064.68
Ref: TM-T201113
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 27 May 2025
SOS1-IN-11
CAS:2654741-64-5
SOS1-IN-11 is an effective inhibitor of SOS1 (IC50 = 30 nM).
Formula:
C22H24F3N5O
Purity:
98.79%
Color and Shape:
Solid
Molecular weight:
431.45
Ref: TM-T60029
| 1mg | 75.00 € | ||
| 5mg | 169.00 € | ||
| 10mg | 284.00 € | ||
| 25mg | 452.00 € | ||
| 50mg | 645.00 € | ||
| 100mg | 867.00 € | ||
| 1mL*10mM (DMSO) | 180.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
GGTI298 Trifluoroacetate
CAS:1217457-86-7
GGTI298 trifluoroacetate (GGTI298TFA salt) is a geranylgeranyltransferase I inhibitor that causes cell cycle arrest and …
Formula:
C27H33N3O3S·C2HF3O2
Purity:
100% - 98.29%
Color and Shape:
Solid
Molecular weight:
593.66
Ref: TM-T6844
| 1mg | 87.00 € | ||
| 5mg | 159.00 € | ||
| 10mg | 240.00 € | ||
| 25mg | 465.00 € | ||
| 50mg | 648.00 € | ||
| 1mL*10mM (DMSO) | 202.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
(R)-BI-2852
CAS:2375482-49-6
(R)-5-hydroxy isoindolin-1-one is an RAS protein inhibitor with antiproliferative and antitumor properties.
Formula:
C31H28N6O2
Purity:
97.78%
Color and Shape:
Soild
Molecular weight:
516.59
Ref: TM-T72084
| 1mg | 93.00 € | ||
| 5mg | 160.00 € | ||
| 10mg | 245.00 € | ||
| 25mg | 395.00 € | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 27 May 2025
KRASG12C IN-14
KRASG12C IN-14 (compound 15), a potent inhibitor specifically designed for the KRAS G12C mutation, exhibits …
Formula:
C51H65F4N9O9S2
Color and Shape:
Solid
Molecular weight:
1088.24
Ref: TM-T200204
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 27 May 2025
(E/Z)-ZINC09659342
CAS:591726-26-0
(E/Z)-ZINC09659342 is an inhibitor of Lbc-Rho A interaction.
Formula:
C23H15F3N2O4
Purity:
95.83%
Color and Shape:
Solid
Molecular weight:
440.37
Ref: TM-T9986
| 1mg | 66.00 € | ||
| 5mg | 145.00 € | ||
| 10mg | 221.00 € | ||
| 25mg | 378.00 € | ||
| 50mg | 533.00 € | ||
| 100mg | 718.00 € | ||
| 200mg | 938.00 € | ||
| 1mL*10mM (DMSO) | 160.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
