CAS 1933528-96-1

MDR-652

CAS: 1933528-96-1

Formula: C₂₂H₂₃ClFN₃O₂S

Purity: 98%

Molecular weight: 447.9533

Ref: IN-DA01V51L

1-((2-(Tert-Butyl)-4-(3-Chlorophenyl)Thiazol-5-Yl)Methyl)-3-(3-Fluoro-4-(Hydroxymethyl)Phenyl)Urea

CAS: 1933528-96-1

1-((2-(Tert-Butyl)-4-(3-Chlorophenyl)Thiazol-5-Yl)Methyl)-3-(3-Fluoro-4-(Hydroxymethyl)Phenyl)Urea

Purity: 98%

Molecular weight: 447.95g/mol

Ref: 54-PC108534

MDR-652

CAS: 1933528-96-1

MDR-652

Purity: ≥95%

Molecular weight: 447.95g/mol

Ref: 54-BUP03574

MDR-652

CAS: 1933528-96-1

MDR-652 is a highly specific and efficacious agonist of nonpungent transient receptor potential vanilloid 1 (TRPV1) with Ki value of 11.4 nM and 23.8 nM for

Formula: C₂₂H₂₃ClFN₃O₂S

Purity: 99.96%

Color and Shape: Solid

Molecular weight: 447.95

Ref: TM-T22360

1-((2-(TERT-BUTYL)-4-(3-CHLOROPHENYL)THIAZOL-5-YL)METHYL)-3-(3-FLUORO-4-(HYDROXYMETHYL)PHENYL)UREA

CAS: 1933528-96-1

Purity: 98%

Molecular weight: 447.9500122

Ref: 10-F840942

MDR-652

CAS: 1933528-96-1

MDR-652 is a novel analgesic that has potential to act as a vanilloid receptor agonist. It is a synthetic, non-opioid, non-NSAID medicine with analgesic activity and the potential to treat neuropathic pain. MDR-652 has been shown to be effective in animal models of neuropathic pain, such as allodynia and mechanical hyperalgesia. MDR-652 also has the ability to cross the skin barrier and reach the systemic circulation. MDR-652 is not active against gram positive bacteria (e.g., Staphylococcus aureus) or anaerobic bacteria (e.g., Clostridium difficile).
MDR-652 also acts on TrpV1 receptors and has been shown in animal models to reduce inflammatory responses in tissues by inhibiting substance P release from sensory nerve endings.

Formula: C₂₂H₂₃ClFN₃O₂S

Purity: Min. 95%

Molecular weight: 448 g/mol

Ref: 3D-ICD52896