CAS 1951-25-3: Amiodarone

Description: Amiodarone is a complex organic compound primarily used as an antiarrhythmic medication to treat various types of cardiac dysrhythmias. Its chemical formula is C25H29I2N, indicating that it contains carbon, hydrogen, iodine, and nitrogen atoms. Amiodarone is characterized by its lipophilic nature, which allows it to accumulate in various tissues, particularly in the lungs, liver, and thyroid. The substance exhibits a long half-life, leading to prolonged effects even after discontinuation of therapy. It functions by inhibiting adrenergic stimulation, prolonging the myocardial action potential, and affecting ion channels, which helps stabilize heart rhythms. Amiodarone is also known for its potential side effects, including thyroid dysfunction, pulmonary toxicity, and skin changes, necessitating careful monitoring during treatment. Its solubility in organic solvents and limited solubility in water are notable physical properties, influencing its formulation and administration routes. Overall, amiodarone is a vital medication in cardiology, but its use requires a thorough understanding of its pharmacokinetics and potential adverse effects.

Formula: C₂₅H₂₉I₂NO₃

InChI: InChI=1S/C25H29I2NO3/c1-4-7-11-22-23(18-10-8-9-12-21(18)31-22)24(29)17-15-19(26)25(20(27)16-17)30-14-13-28(5-2)6-3/h8-10,12,15-16H,4-7,11,13-14H2,1-3H3

InChI key: InChIKey=IYIKLHRQXLHMJQ-UHFFFAOYSA-N

SMILES: O=C(C1=CC(I)=C(OCCN(CC)CC)C(I)=C1)C=2C=3C=CC=CC3OC2CCCC

Synonyms:

• (2-Butyl-1-Benzofuran-3-Yl){4-[2-(Diethylamino)Ethoxy]-3,5-Diiodophenyl}Methanone
• (2-Butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone
• 2-Butyl-3-[3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl]benzofuran
• 2-Butyl-3-benzofuranyl p-[(2-diethylamino)ethoxy]-m,m-diiodophenyl ketone
• 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran
• 2-n-Butyl-3′,5′-diiodo-4′-N-diethylaminoethoxy-3-benzoylbenzofuran
• 2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-diiodophenoxy}-N,N-diethylethanaminium chloride
• Amidorone
• Amiodaron
• Amiodarona
• Amiodarone Base
• Ancaron
• Ketone, 2-butyl-3-benzofuranyl 4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl
• Methanone, (2-butyl-3-benzofuranyl)(4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl)-
• Sedacoron
• Sedacorone
• Amiodarone

Amiodarone Hydrochloride

CAS: 1951-25-319774-82-4

• Formula: C₂₅H₂₉I₂NO₃·HCl
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 681.78

Amiodarone

CAS: 1951-25-3

• Formula: C₂₅H₂₉I₂NO₃
• Purity: 98%
• Color and Shape: Liquid
• Molecular weight: 645.3116

Amiodarone

CAS: 1951-25-3

• Formula: C₂₅H₂₉I₂NO₃
• Purity: ≥ 96.0%
• Color and Shape: Colourless to pale yellow oil or solid
• Molecular weight: 645.31

Amiodarone

CAS: 1951-25-3

Amiodarone (Cordarone) is an antiarrhythmic compound that induces pulmonary toxicity and inhibits ATP-sensitive potassium channels.

• Formula: C₂₅H₂₉I₂NO₃
• Purity: 98.09%
• Color and Shape: Crystalline Powder; Crystals From Acetone Solid
• Molecular weight: 645.31

Amiodarone

CAS: 1951-25-3

Applications Amiodarone is a non-selective ion channel blocker. Antiarrhythmic (class III). References Bonati, M., et …

• Formula: C₂₅H₂₉I₂NO₃
• Color and Shape: Colourless To Light Yellow
• Molecular weight: 645.31

Amiodarone

CAS: 1951-25-3

Versatile small molecule scaffold

• Formula: C₂₅H₂₉I₂NO₃
• Purity: Min. 95%
• Molecular weight: 645.31 g/mol