CAS 19774-82-4
:Amiodarone hydrochloride
Description:
Amiodarone hydrochloride is a synthetic antiarrhythmic medication primarily used to treat various types of cardiac arrhythmias, particularly ventricular tachycardia and atrial fibrillation. It is classified as a Class III antiarrhythmic agent, which means it works by prolonging the action potential duration and refractory period in myocardial tissue. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for intravenous administration. Its chemical structure includes a benzofuran moiety, which contributes to its pharmacological properties. Amiodarone hydrochloride exhibits a long half-life, allowing for sustained therapeutic effects, but it may also lead to potential side effects, including thyroid dysfunction, pulmonary toxicity, and skin changes. Due to its complex pharmacokinetics, careful monitoring of patients is essential during treatment. The CAS number 19774-82-4 uniquely identifies this compound in chemical databases, facilitating research and regulatory processes.
Formula:C25H29I2NO3·ClH
InChI:InChI=1S/C25H29I2NO3.ClH/c1-4-7-11-22-23(18-10-8-9-12-21(18)31-22)24(29)17-15-19(26)25(20(27)16-17)30-14-13-28(5-2)6-3;/h8-10,12,15-16H,4-7,11,13-14H2,1-3H3;1H
InChI key:InChIKey=ITPDYQOUSLNIHG-UHFFFAOYSA-N
SMILES:C(=O)(C=1C=2C(OC1CCCC)=CC=CC2)C3=CC(I)=C(OCCN(CC)CC)C(I)=C3.Cl
Synonyms:- 2-Butyl-3-benzofuranyl 4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone hydrochloride
- Amiodar
- Amiodarone hydrochlorde
- Amiodarone hydrochloride
- Amiodaronum hydrochloride
- Ancoron
- Angiodarona
- Atlansil
- Cordarex
- Cordarone
- Cordarone X
- Ketone, 2-butyl-3-benzofuranyl 4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl, hydrochloride
- L 3428
- L 3428-Labaz
- Methanone, (2-butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]-, hydrochloride
- Methanone, (2-butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]-, hydrochloride (1:1)
- Miocard
- Miodaron
- Nexterone
- Ortacrone
- Pacerone
- Ritmocardyl
- Rythmarone
- Skf 33134A
- See more synonyms
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Amiodarone Hydrochloride
CAS:Formula:C25H29I2NO3·HClPurity:>98.0%(HPLC)(T)Color and Shape:White to Almost white powder to crystalMolecular weight:681.78Amiodarone hydrochloride
CAS:A non-selective ion channel blocker; also an antiarrhythmic agentFormula:C25H29I2NO3•HClMolecular weight:681.77Amiodarone hydrochloride
CAS:Amiodarone hydrochlorideFormula:C25H29I2NO3HClPurity:99.6%Color and Shape:WhiteMolecular weight:681.00037Amiodarone Hydrochloride
CAS:Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoiFormula:C25H29I2NO3·HClColor and Shape:White PowderMolecular weight:681.77Amiodarone hydrochloride
CAS:Amiodarone hydrochlorideFormula:C25H29I2NO3·ClHPurity:>98%Color and Shape:SolidMolecular weight:681.77Amiodarone hydrochloride
CAS:Amiodarone HCl: Antianginal, class III antiarrhythmic. Lengthens heart muscle action, slows heart rate, reduces vascular resistance.Formula:C25H30ClI2NO3Purity:99.81% - 99.98%Color and Shape:White SolidMolecular weight:681.773Amiodarone hydrochloride
CAS:Amiodarone hydrochlorideFormula:C25H29I2NO3·HClPurity:99.5%Molecular weight:681.78Amiodarone HCl
CAS:Formula:C25H29I2NO3·HClColor and Shape:White To Off-White SolidMolecular weight:645.32 36.46Amiodarone hydrochloride
CAS:Formula:C25H29I2NO3·HClPurity:≥ 98.0%Color and Shape:White to off-white crystalline powderMolecular weight:681.77Amiodarone hydrochloride
CAS:Controlled ProductFormula:C25H29I2NO3·ClHColor and Shape:NeatMolecular weight:681.77Amiodarone Hydrochloride 1.0 mg/ml in Methanol (as free base)
CAS:Formula:C25H29I2NO3·ClHColor and Shape:Single SolutionMolecular weight:681.77Amiodarone Hydrochloride 1.0 mg/ml in Methanol (as free base)
CAS:Formula:C25H29I2NO3·ClHColor and Shape:ColourlessMolecular weight:681.77Amiodarone Hydrochloride
CAS:Controlled ProductFormula:C25H29I2NO3·ClHColor and Shape:NeatMolecular weight:681.77Amiodarone HCl
CAS:(2-Butylbenzofuran-3-yl)(4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl)methanone hydrochlorideFormula:C25H30ClI2NO3Purity:97%Molecular weight:681.77Amiodarone HCl
CAS:Amiodarone a class III anti-arrhythmic agent, used to treat and prevent certain types of irregular heartbeats. It is a competitor for natural ligands of alpha and beta adrenergic receptors, muscarinic acetylcholine receptors, histamine H1 receptors, and serotonin 5HT2A/5HT2C receptors. Amiodarone has been shown to reduce the number of atrial and ventricular arrhythmias in patients with structural heart disease, and has been used to treat atrial fibrillation, ventricular tachycardia, and Wolff-Parkinson-White Syndrome. It has also been used in the prevention of myocardial infarcts due to its ability to modify blood pressure and maintain cardiac function. In addition, amiodarone inhibits prostaglandin synthesis by inhibiting cyclooxygenase enzymes. This prevents inflammation in the gastrointestinal tract and reduces bowel disease symptoms such as cramping or diarrhea.
Formula:C25H30ClI2NO3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:681.77 g/mol
