CAS 1953-04-4: Galantamine hydrobromide

Description: Galantamine hydrobromide is a reversible inhibitor of the enzyme acetylcholinesterase, primarily used in the treatment of mild to moderate Alzheimer's disease and other cognitive disorders. It is a quaternary ammonium compound derived from the snowdrop plant and exhibits a dual mechanism of action by enhancing cholinergic function and modulating nicotinic receptors. The substance appears as a white to off-white crystalline powder, is soluble in water, and has a molecular formula that reflects its complex structure. Galantamine hydrobromide is typically administered orally and is known for its ability to improve cognitive function and memory in patients. Its pharmacokinetics involve absorption, distribution, metabolism, and excretion processes that are influenced by factors such as age and liver function. Common side effects may include nausea, vomiting, and diarrhea, which are generally mild. As with any medication, it is essential to use galantamine hydrobromide under medical supervision to monitor for efficacy and potential adverse reactions.

Formula: C₁₇H₂₁NO₃·BrH

InChI: InChI=1S/C17H21NO3.BrH/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17;/h3-6,12,14,19H,7-10H2,1-2H3;1H/t12-,14-,17-;/m0./s1

InChI key: InChIKey=QORVDGQLPPAFRS-XPSHAMGMSA-N

SMILES: Br.OC1C=CC23C4=C(OC2C1)C(OC)=CC=C4CN(C)CC3

Synonyms:

• (4aS,6R,8aS)-6-hydroxy-3-methoxy-11-methyl-5,6,9,10,11,12-hexahydro-4aH-[1]benzofuro[3a,3,2-ef][2]benzazepin-11-ium
• 5A,6,7,8,8A,12B-Hexahydrogalanthamine Hydrobromide (1:1)
• 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, hydrobromide (1:1), (4aS,6R,8aS)-
• 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, hydrobromide, (4aS,6R,8aS)-
• Galantamine Hbr
• Galantamine Hydrobromide
• Galanthamine HBr
• Galanthamine Hydrobromide (1:1)
• Galanthamine hydrogen bromide
• Jilkon hydrobromide
• Lycoremine hydrobromide
• Nivalin
• Nivaline
• Nivaline (pharmaceutical)
• Razadyne
• Reminyl
• Tamilin
• Galanthamine, hydrobromide

Galantamine Hydrobromide

CAS: 1953-04-4357-70-0

• Formula: C₁₇H₂₁NO₃·HBr
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 368.27

Galanthamine hydrobromide

CAS: 1953-04-4

Centrally active and long-acting acetylcholinesterase inhibitor This Thermo Scientific Chemicals brand product was originally part …

• Formula: C₁₇H₂₁NO₃•HBr
• Molecular weight: 368.27

Galantamine hydrobromide impurity standard

CAS: 1668-85-5 1953-04-4199014-26-1 60755-80-8

• Color and Shape: White Powder

Galantamine hydrobromide

CAS: 1953-04-4

• Formula: C₁₇H₂₁NO₃
• Purity: 77.4%
• Color and Shape: White
• Molecular weight: 287.15214

Galantamine synthetic for system suitability CRS

CAS: 1953-04-4

• Formula: C₁₇H₂₂BrNO₃
• Molecular weight: 368.2655

Galantamine hydrobromide CRS

CAS: 1953-04-4

• Formula: C₁₇H₂₂BrNO₃
• Molecular weight: 368.2655

Galantamine natural for system suitability CRS

CAS: 1953-04-4

• Formula: C₁₇H₂₂BrNO₃
• Color and Shape: Crystalline Powder. White. Amorphous.
• Molecular weight: 368.2655

Galantamine Hydrobromide

CAS: 1953-04-469353-21-5

Other alkaloids,natural or reproduced by synthesis, and their salts, ethers,esters&other derivatives, nesoi

• Formula: C₁₇H₂₁NO₃·BrH
• Color and Shape: White Powder
• Molecular weight: 367.07831

(4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol hydrobromide

CAS: 1953-04-4

• Formula: C₁₇H₂₂BrNO₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 368.2655

Galanthamine hydrobromide

CAS: 1953-04-4

Galanthamine hydrobromide (Galantamine hydrobromide), a long-acting and centrally active AChE inhibitor (IC50:410 nM), is an …

• Formula: C₁₇H₂₁NO₃·HBr
• Purity: 98% - 99.49%
• Color and Shape: White To Off-White Powder
• Molecular weight: 368.27

Galanthamine hydrobromide

CAS: 1953-04-4

• Formula: C₁₇H₂₁NO₃HBr
• Purity: ≥ 98.0%
• Color and Shape: White powder
• Molecular weight: 368.27

Galanthamine hydrobromide

CAS: 1953-04-4

• Purity: 99.19%
• Molecular weight: 368.27g/mol

Galantamine HBr

CAS: 1953-04-4

• Formula: C₁₇H₂₁NO₃·HBr
• Color and Shape: White To Off-White Solid
• Molecular weight: 287.36 80.91

Galantamine-d3 HBr

CAS: 1953-04-4

• Formula: C₁₇H₁₈D₃NO₃·HBr
• Color and Shape: White To Off-White Solid
• Molecular weight: 290.38 80.91

Galanthamine hydrobromide

CAS: 1953-04-4

• Formula: C₁₇H₂₂BrNO₃
• Purity: 95%~99%
• Molecular weight: 368.271

Galantamine Hydrobromide

CAS: 1953-04-4

• Formula: C₁₇H₂₁NO₃·BrH
• Color and Shape: Neat
• Molecular weight: 368.27

Galantamine hydrobromide

CAS: 1953-04-4

• Formula: C₁₇H₂₁NO₃·BrH
• Color and Shape: Neat
• Molecular weight: 368.27

Galanthamine hydrobromide

CAS: 1953-04-4

Natural alkaloid

• Formula: C₁₇H₂₁NO₃HBr
• Purity: ≥ 95.0 % (HPLC)
• Color and Shape: Powder
• Molecular weight: 368.27

Galanthamine Hydrobromide

CAS: 1953-04-4

Applications A selective acetylcholinesterase inhibitor. A therapeutic agent for the treatment and prevention of Alzheimer's …

• Formula: C₁₇H₂₁NO₃·BrH
• Color and Shape: White To Off-White
• Molecular weight: 368.27

Galanthamine hydrobromide

CAS: 1953-04-4

A reversible and competitive inhibitor of acetylcholinesterase (AChE) that is approved for the treatment of …

• Formula: C₁₇H₂₁NO₃·HBr
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 368.27 g/mol