CAS 1953-04-4
:Galantamine hydrobromide
Description:
Galantamine hydrobromide is a reversible inhibitor of the enzyme acetylcholinesterase, primarily used in the treatment of mild to moderate Alzheimer's disease and other cognitive disorders. It is a quaternary ammonium compound derived from the snowdrop plant and exhibits a dual mechanism of action by enhancing cholinergic function and modulating nicotinic receptors. The substance appears as a white to off-white crystalline powder, is soluble in water, and has a molecular formula that reflects its complex structure. Galantamine hydrobromide is typically administered orally and is known for its ability to improve cognitive function and memory in patients. Its pharmacokinetics involve absorption, distribution, metabolism, and excretion processes that are influenced by factors such as age and liver function. Common side effects may include nausea, vomiting, and diarrhea, which are generally mild. As with any medication, it is essential to use galantamine hydrobromide under medical supervision to monitor for efficacy and potential adverse reactions.
Formula:C17H22BrNO3
InChI:InChI=1/C17H21NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,12,14,19H,7-10H2,1-2H3/p+1/t12-,14-,17-/m0/s1
InChI key:InChIKey=QORVDGQLPPAFRS-XPSHAMGMSA-N
SMILES:O(C)C1=C2C=3[C@]4([C@@](O2)(C[C@@H](O)C=C4)[H])CCN(C)CC3C=C1.Br
Synonyms:- (4aS,6R,8aS)-6-hydroxy-3-methoxy-11-methyl-5,6,9,10,11,12-hexahydro-4aH-[1]benzofuro[3a,3,2-ef][2]benzazepin-11-ium
- 5A,6,7,8,8A,12B-Hexahydrogalanthamine Hydrobromide (1:1)
- 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, hydrobromide (1:1), (4aS,6R,8aS)-
- 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, hydrobromide, (4aS,6R,8aS)-
- Galantamine Hbr
- Galantamine Hydrobromide
- Galanthamine HBr
- Galanthamine Hydrobromide (1:1)
- Galanthamine hydrogen bromide
- Jilkon hydrobromide
- Lycoremine hydrobromide
- Nivalin
- Nivaline
- Nivaline (pharmaceutical)
- Razadyne
- Reminyl
- Tamilin
- Galanthamine, hydrobromide
- GALANTHAMINE HYDROBROMIDUM
- Galanthamine Hydrobromide Injection
- Hydrobromic acid·galanthamine
- 4A,5,9,10,11,12-HEXAHYDRO-3-METHOXY-11-METHYL-6H-BENZOFURO[3A,3,2-EF][2]BENZAZEPIN-6-OL HYDROBROMIDE
- NIVALIN, HBR
- (-)-Galanthaminium bromide
- GALANTHAMIDE HYDROBROMIDE
- galanthamine hydrobromide from lycoris sp.
- See more synonyms
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Galantamine Hydrobromide
CAS:Formula:C17H21NO3·HBrPurity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:368.27Galanthamine hydrobromide
CAS:<p>Centrally active and long-acting acetylcholinesterase inhibitor</p>Formula:C17H21NO3•HBrMolecular weight:368.27Galantamine hydrobromide impurity standard
CAS:Galantamine hydrobromide impurity standardColor and Shape:White PowderGalantamine hydrobromide
CAS:Galantamine hydrobromideFormula:C17H21NO3Purity:77.4%Color and Shape:WhiteMolecular weight:287.15214GALANTAMINE HYDROBROMIDE CRS
CAS:<p>GALANTAMINE HYDROBROMIDE CRS</p>Formula:C17H22BrNO3Molecular weight:368.2655GALANTAMINE NATURAL FOR SYSTEM SUITABILITY CRS
CAS:<p>GALANTAMINE NATURAL FOR SYSTEM SUITABILITY CRS</p>Formula:C17H22BrNO3Color and Shape:Crystalline Powder. White. Amorphous.Molecular weight:368.2655GALANTAMINE SYNTHETIC FOR SYSTEM SUITABILITY CRS
CAS:<p>GALANTAMINE SYNTHETIC FOR SYSTEM SUITABILITY CRS</p>Formula:C17H22BrNO3Molecular weight:368.2655Galantamine Hydrobromide
CAS:Other alkaloids,natural or reproduced by synthesis, and their salts, ethers,esters&other derivatives, nesoiFormula:C17H21NO3·BrHColor and Shape:White PowderMolecular weight:367.07831(4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol hydrobromide
CAS:Formula:C17H22BrNO3Purity:98%Color and Shape:SolidMolecular weight:368.2655Galanthamine hydrobromide
CAS:<p>Galanthamine hydrobromide (Galantamine hydrobromide), a long-acting and centrally active AChE inhibitor (IC50:410 nM), is an allosteric potentiator at neuronal</p>Formula:C17H21NO3·HBrPurity:98% - 99.49%Color and Shape:White To Off-White PowderMolecular weight:368.27Galantamine HBr
CAS:Formula:C17H21NO3·HBrColor and Shape:White To Off-White SolidMolecular weight:287.36 80.91Galanthamine hydrobromide
CAS:Formula:C17H21NO3HBrPurity:≥ 98.0%Color and Shape:White powderMolecular weight:368.27Galantamine hydrobromide
CAS:Controlled ProductFormula:C17H21NO3·BrHColor and Shape:White To Off-WhiteMolecular weight:368.27Galantamine Hydrobromide
CAS:Controlled ProductFormula:C17H21NO3·BrHColor and Shape:White To Off-WhiteMolecular weight:368.27Galanthamine hydrobromide
CAS:Natural alkaloidFormula:C17H21NO3HBrPurity:≥ 95.0 % (HPLC)Color and Shape:PowderMolecular weight:368.27Galanthamine Hydrobromide
CAS:Controlled Product<p>Applications A selective acetylcholinesterase inhibitor. A therapeutic agent for the treatment and prevention of Alzheimer's disease and other diseases resulting from reduced neuronal metabolism.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Friess, S.L., et al.: Toxicol. Appl. Pharmacol., 3, 347 (1961), Bickel, U., et al.: Clin. Pharmacol. Ther., 50, 420 (1991), Harvey, A.L., et al.: Pharmacol. Ther., 68, 113 (1995),<br></p>Formula:C17H21NO3·BrHColor and Shape:White To Off-WhiteMolecular weight:368.27Galanthamine hydrobromide
CAS:Controlled Product<p>A reversible and competitive inhibitor of acetylcholinesterase (AChE) that is approved for the treatment of Alzheimer’s disease. It is also an allosteric modulator of nicotinic acetylcholine receptors (nAChR). Activation of nAChR along with upregulation of anti-apoptotic protein Bcl-2 prevents apoptosis and therefore provides neuroprotection.</p>Formula:C17H21NO3·HBrPurity:Min. 95%Color and Shape:PowderMolecular weight:368.27 g/mol
![(4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0034YM.jpg&w=3840&q=75)
