CAS 196309-76-9

(2E)-3-[(4-tert-butylphenyl)sulfonyl]prop-2-enenitrile

Description:

(2E)-3-[(4-tert-butylphenyl)sulfonyl]prop-2-enenitrile is an organic compound characterized by its unique structural features, including a prop-2-enenitrile backbone and a sulfonyl group attached to a tert-butylphenyl moiety. This compound exhibits a conjugated double bond system, which can contribute to its reactivity and potential applications in organic synthesis and materials science. The presence of the sulfonyl group enhances its polarity and solubility in polar solvents, while the bulky tert-butyl group may influence its steric properties and stability. Additionally, the nitrile functional group introduces a strong dipole moment, making the compound useful in various chemical reactions, such as nucleophilic additions or as a building block in the synthesis of more complex molecules. Overall, this compound's distinctive features make it a subject of interest in both academic research and industrial applications, particularly in the fields of pharmaceuticals and agrochemicals.

Formula: C₁₃H₁₅NO₂S

InChI: InChI=1/C13H15NO2S/c1-13(2,3)11-5-7-12(8-6-11)17(15,16)10-4-9-14/h4-8,10H,1-3H3/b10-4+

InChI key: InChIKey=VHKZGNPOHPFPER-ONNFQVAWSA-N

SMILES: S(/C=C/C#N)(=O)(=O)C1=CC=C(C(C)(C)C)C=C1

Synonyms:

• (2E)-3-[(4-tert-Butylphenyl)sulfonyl]acrylonitrile
• (2E)-3-[[4-(1,1-Dimethylethyl)phenyl]sulfonyl]-2-propenenitrile
• 2-Propenenitrile, 3-[[4-(1,1-dimethylethyl)phenyl]sulfonyl]-, (2E)-
• 2-Propenenitrile, 3-[[4-(1,1-dimethylethyl)phenyl]sulfonyl]-, (E)-
• Bay 11-70585
• Bay 11-7085
• Bay 117083
• BAY 11-7085 USP/EP/BP
• (E)-3-(T-BUTYLPHENYLSULFONYL)-2-PROPENENITRILE
• CS-1876
• (E)-3-(4-tert-butylphenylsulfonyl)acrylonitrile
• BAY 117083 (2E)-3-[[4-(1,1-Dimethylethyl)phenyl]sulfonyl]-2-propenenitrile
• (E)3-[(4-T-BUTYLPHENYL)SULFONYL]-2-PROPENENITRILE
• (E)-3-(4-tert-butylphenyl)sulfonylprop-2-enenitrile
• BAY 11-7085 - CAS 196309-76-9 - Calbiochem
• (2E)-3-[[4-(1,1-Dimethylethyl)phenyl]sulfonyl]-2-propenenitrile BAY 11-7085
• BAY117085;BAY11-7085

BAY 11-7085

CAS: 196309-76-9

Formula: C₁₃H₁₅NO₂S

Purity: >97.0%(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 249.33

Ref: 3B-B4845

(E)-3-((4-(tert-Butyl)phenyl)sulfonyl)acrylonitrile

CAS: 196309-76-9

Formula: C₁₃H₁₅NO₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 249.3287

Ref: IN-DA0073VJ

Bay 11-7085

CAS: 196309-76-9

Formula: C₁₃H₁₅NO₂S

Molecular weight: 249.33

Ref: 7W-GK6962

Bay 11-7085

CAS: 196309-76-9

Bay 11-7085

Purity: ≥98%

Molecular weight: 249.33g/mol

Ref: 54-BUP09664

(E)-3-((4-(Tert-Butyl)Phenyl)Sulfonyl)Acrylonitrile

CAS: 196309-76-9

(E)-3-((4-(Tert-Butyl)Phenyl)Sulfonyl)Acrylonitrile

Purity: 97%

Molecular weight: 249.33g/mol

Ref: 54-OR1023777

Bay 11-7085

CAS: 196309-76-9

Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).

Formula: C₁₃H₁₅NO₂S

Purity: 99.76% - 99.94%

Color and Shape: White Solid

Molecular weight: 249.33

Ref: TM-T1934

(E)-3-((4-(tert-Butyl)phenyl)sulfonyl)acrylonitrile

CAS: 196309-76-9

Formula: C₁₃H₁₅NO₂S

Purity: 98%

Molecular weight: 249.33

Ref: 10-F325877

BAY 11-7085

Controlled Product

CAS: 196309-76-9

Applications BAY 11-7085 is a NF-κB (nuclear factor-κB) inhibitor and can be used as a therapeutic agent for the treatment of endometriosis. BAY 11-7085 inhibits the cell proliferation and DNA synthesis of endometriotic cyst stromal cells (ECSCs) and induces apoptosis by surpressing antiapoptotic proteins.
References Berger, N., et al.: Exp. Hematol., 35, 1495 (2007); Nasu, K., et al.: Am. J. Physiol., 293, E16 (2007)

Formula: C₁₃H₁₅NO₂S

Color and Shape: Neat

Molecular weight: 249.33

Ref: TR-B118795

Bay 11-7085

CAS: 196309-76-9

Bay 11-7085 is a synthetic chemical inhibitor that is utilized in scientific research. It is derived from a class of bioactive molecules designed to interfere with specific cellular pathways. Bay 11-7085 functions as a covalent inhibitor of the NF-κB signaling pathway, a critical regulator of immune response and cell survival. By targeting the phosphorylation of IκBα, Bay 11-7085 effectively prevents the translocation of NF-κB to the nucleus, thereby modulating gene expression and inhibiting downstream effects.

Formula: C₁₃H₁₅NO₂S

Purity: Min. 95%

Molecular weight: 249.33 g/mol

Ref: 3D-WHA30976