CAS 19660-77-6

Chlorin e6

Description:

Chlorin e6, also known as chlorin e6 or chlorin e6 (C6H6N4O4), is a chlorophyll derivative that exhibits unique photophysical and photochemical properties, making it valuable in various applications, particularly in photodynamic therapy (PDT) and as a photosensitizer. This compound is characterized by its ability to absorb light in the visible spectrum, particularly in the red region, which enhances its effectiveness in therapeutic applications. Chlorin e6 is known for its high singlet oxygen generation efficiency upon light activation, which is crucial for inducing cytotoxic effects in targeted cancer cells. Additionally, it possesses a relatively high solubility in organic solvents, which facilitates its use in formulations for medical and research purposes. Its structural features include a central porphyrin-like core with various substituents that influence its reactivity and interaction with biological systems. Overall, Chlorin e6 is a promising compound in the fields of medicine and biotechnology, particularly for its potential in cancer treatment and imaging applications.

Formula: C₃₄H₃₆N₄O₆

InChI: InChI=1S/C34H36N4O6/c1-7-19-15(3)23-12-25-17(5)21(9-10-29(39)40)32(37-25)22(11-30(41)42)33-31(34(43)44)18(6)26(38-33)14-28-20(8-2)16(4)24(36-28)13-27(19)35-23/h7,12-14,17,21,35,38H,1,8-11H2,2-6H3,(H,39,40)(H,41,42)(H,43,44)/b23-12?,24-13-,25-12-,26-14-,27-13?,28-14?,32-22?,33-22-/t17-,21-/m0/s1

InChI key: InChIKey=VAJLRIOJDADNAT-QXILTCMVSA-N

SMILES: C(C(O)=O)C1=C2[C@@H](CCC(O)=O)[C@H](C)C(=N2)C=C3NC(C(C=C)=C3C)=CC4=NC(=CC=5NC1=C(C(O)=O)C5C)C(CC)=C4C

Synonyms:

• (17S,18S)-18-(2-carboxyethyl)-20-(carboxymethyl)-12-ethenyl-7-ethyl-3,8,13,17-tetramethyl-17,18-dihydroporphyrin-2-carboxylic acid
• (7S,8S)-3-Carboxy-5-(carboxymethyl)-13-ethenyl-18-ethyl-7,8-dihydro-2,8,12,17-tetramethyl-21H,23H-porphine-7-propanoic acid
• 18-(2-Carboxyethyl)-20-(Carboxymethyl)-12-Ethenyl-7-Ethyl-3,8,13,17-Tetramethyl-17,18-Dihydroporphyrin-2-Carboxylic Acid
• 2-Porphinepropionic acid, 18-carboxy-20-(carboxymethyl)-13-ethyl-2β,3-dihydro-3β,7,12,17-tetramethyl-8-vinyl-
• 21H,23H-Porphine-2-propanoic acid, 18-carboxy-20-(carboxymethyl)-8-ethenyl-13-ethyl-2,3-dihydro-3,7,12,17-tetramethyl-,(2S-trans)-
• 21H,23H-Porphine-7-propanoic acid, 3-carboxy-5-(carboxymethyl)-13-ethenyl-18-ethyl-7,8-dihydro-2,8,12,17-tetramethyl-, (7S,8S)-
• Chlorin a₆
• Chlorin e6
• Chlorin e₆
• Chlorine a₆
• Chlorine e₆
• Chlorophyllin
• Photochlorine
• Photolon
• Phytochlorin
• Phytochlorin e₆
• Phytochlorine e₆
• (2S-trans)-18-Carboxy-20-(carboxymethyl)-13-ethyl-2,3-dihydro-3,7,12,17-tetramethyl-8-vinyl-21H,23H-porphine-2-propionic acid

21H,23H-Porphine-7-propanoic acid,3-carboxy-5-(carboxymethyl)-13-ethenyl-18-ethyl-7,8-dihydro-2,8,12,17-tetramethyl-, (7S,8S)-

CAS: 19660-77-6

Formula: C₃₄H₃₈N₄O₆

Purity: 90%

Color and Shape: Solid

Molecular weight: 598.6887

Ref: IN-DA00I3KS

Chlorin e6

CAS: 19660-77-6

Chlorin e6

Formula: C₃₄H₃₆N₄O₆

Purity: 90%

Color and Shape: light brown to black solid

Molecular weight: 596.67g/mol

Ref: 54-OR61545

Chlorin E6

CAS: 19660-77-6

Chlorin E6

Purity: ≥90%

Molecular weight: 596.67g/mol

Ref: 54-BUP06858

Chlorin e6

CAS: 19660-77-6

Formula: C₃₄H₃₆N₄O₆

Purity: 93%-98%

Color and Shape: Ce

Molecular weight: 596.673

Ref: FT-Ce6

Chlorin e6

CAS: 19660-77-6

Formula: C₃₄H₃₆N₄O₆

Purity: 93%-98%

Color and Shape: Ce

Molecular weight: 596.673

Ref: FT-CE6

Chlorin E6

Controlled Product

CAS: 19660-77-6

Applications Chlorin E6 is a photosensitizer.The conjugates of gold nanorods and chlorin e6 enhance the fluorescence detection and photodynamic therapy (PDT) of cancers.
References Schmidt-Erfurth, U., et al.: Brit. J. Cancer, 75, 54 (1997); Huang, X., et al.: Phys. Chem. Chem. Phys., 15, 15727 (2013)

Formula: C₃₄H₃₆N₄O₆

Color and Shape: Neat

Molecular weight: 596.67

Ref: TR-C380285

Chlorin E6

CAS: 19660-77-6

CE6 is a photosensitizer effective against tumors with light exposure, shown successful in mouse models and human trials for bronchial and lung cancer.

Formula: C₃₄H₃₆N₄O₆

Purity: 90.964% - 95.05%

Color and Shape: Solid

Molecular weight: 596.67

Ref: TM-T36466

Chlorin e6

CAS: 19660-77-6

Chlorin e6 is a photosensitizer, which is derived from chlorophyll, specifically the breakdown products of chlorophyll a extracted from plants and algae. It has a significant absorption in the red and near-infrared region of the electromagnetic spectrum, facilitating its use in photodynamic therapy (PDT). Upon activation by light, chlorin e6 produces reactive oxygen species, including singlet oxygen, which can induce cell death. This photochemical mechanism allows for the targeted destruction of cancer cells when used in oncological settings.

Formula: C₃₄H₃₆N₄O₆

Purity: 90%Min

Color and Shape: Dark Blue-Green Or Dark Purple Solid

Molecular weight: 596.67 g/mol

Ref: 3D-FC145291

Chlorin e6

CAS: 19660-77-6

Purity: 90%

Molecular weight: 596.684021

Ref: 10-F868774