CAS 197720-53-9: 10H,13H-Benzo[de]pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-10,13-dione, 1-amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-, (1S-trans)-, methanesulfonate (1:1) (salt), dihydrate

Description: The chemical substance known as "10H,13H-Benzo[de]pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-10,13-dione, 1-amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-, (1S-trans)-, methanesulfonate (1:1) (salt), dihydrate" with CAS number 197720-53-9 is a complex organic compound characterized by its intricate polycyclic structure, which includes fused aromatic rings and various functional groups. This compound features a methanesulfonate salt form, indicating it has been neutralized with methanesulfonic acid, enhancing its solubility in polar solvents. The presence of a fluorine atom and multiple hydroxy and amino groups suggests potential biological activity, possibly as a pharmaceutical agent. The dihydrate form indicates that the compound can incorporate water molecules into its crystalline structure, which may influence its stability and solubility. Overall, this substance's unique structural features and functional groups may contribute to its reactivity and potential applications in medicinal chemistry or related fields.

Formula: C₂₄H₂₂FN₃O₄·CH₄O₃S·2H₂O

InChI: InChI=1S/C24H22FN3O4.CH4O3S.H2O/c1-3-24(31)14-6-18-21-12(8-28(18)22(29)13(14)9-32-23(24)30)19-16(26)5-4-11-10(2)15(25)7-17(27-21)20(11)19;1-5(2,3)4;/h6-7,16,31H,3-5,8-9,26H2,1-2H3;1H3,(H,2,3,4);1H2/t16-,24-;;/m0../s1

InChI key: InChIKey=UJUAXEHQNOWJTE-RLBKRBMPSA-N

SMILES: O=C1C2=C(C=C3C=4N=C5C=C(F)C(=C6C5=C(C4CN13)C(N)CC6)C)C(O)(C(=O)OC2)CC.O=S(=O)(O)C.O

Synonyms:

• Exatecan mesylate hydrate
• 10H,13H-Benzo[de]pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-10,13-dione, 1-amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-, (1S-trans)-, methanesulfonate (1:1) (salt), dihydrate

Exatecan mesylate dihydrate

CAS: 197720-53-9

Exatecan mesylate dihydrate (DX-8951), a DNA topoisomerase I inhibitor, exhibits an IC50 of 2.2 μM …

• Formula: C₂₅H₃₀FN₃O₉S
• Purity: 98%
• Color and Shape: Liquid
• Molecular weight: 567.58

Exatecan mesylate

CAS: 197720-53-9

Please enquire for more information about Exatecan mesylate including the price, delivery time and more …

• Formula: C₂₅H₃₀FN₃O₉S
• Purity: Min. 95%
• Molecular weight: 567.6 g/mol