CAS 1977495-97-8

Formula: C24H32Cl2N8O

InChI: InChI=1S/C24H30N8O.2ClH/c1-30-9-11-31(12-10-30)18-5-6-20(25-15-18)28-23-26-14-17-13-19-22(33)27-16-24(7-3-2-4-8-24)32(19)21(17)29-23;;/h5-6,13-15H,2-4,7-12,16H2,1H3,(H,27,33)(H,25,26,28,29);2*1H

InChI key: BRCYOXKEDFAUSA-UHFFFAOYSA-N

SMILES: CN1CCN(CC1)C2=CN=C(C=C2)NC3=NC=C4C=C5C(=O)NCC6(N5C4=N3)CCCCC6.Cl.Cl

Trilaciclib hydrochloride

CAS: 1977495-97-8

Trilaciclib hydrochloride (G1T28 hydrochloride) is an inhibitor of CDK4/6 (IC50s: 1 nM and 4 nM for CDK4 and CDK6).

Formula: C₂₄H₃₂Cl₂N₈O

Purity: 99.69% - 99.89%

Color and Shape: Solid

Molecular weight: 519.47

Ref: TM-T13202

7',8'-Dihydro-2'-[[5-(4-methyl-1-piperazinyl)-2-pyridinyl]amino]spiro[cyclohexane-1,9'(6'H)-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyrimidin]-6'-one dihydrochloride

CAS: 1977495-97-8

Formula: C₂₄H₃₂Cl₂N₈O

Purity: 99%

Color and Shape: Solid

Molecular weight: 519.4699

Ref: IN-DA01EOQ0

Trilaciclib DiHCl

CAS: 1977495-97-8

Formula: C₂₄H₃₀N₈O·2HCl

Molecular weight: 446.56 2*36.46

Ref: 4Z-T-474001

Trilaciclib hydrochloride

CAS: 1977495-97-8

Trilaciclib hydrochloride

Formula: C₂₄H₃₂Cl₂N₈O

Purity: 99.5%

Color and Shape: Solid

Molecular weight: 519.47

Ref: 54-BUP08915

Trilaciclib HCl

CAS: 1977495-97-8

2'-((5-(4-Methylpiperazin-1-yl)pyridin-2-yl)amino)-7',8'-dihydro-6'H-spiro[cyclohexane-1,9'-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyrimidin]-6'-one dihydrochloride

Formula: C₂₄H₃₂Cl₂N₈O

Purity: 99%

Molecular weight: 519.47

Ref: IN-DG768616

Trilaciclib hydrochloride

CAS: 1977495-97-8

Trilaciclib is a small molecule that inhibits the CDK4/6 complex and is an inhibitor of cell proliferation. It has been shown to inhibit cancer growth in vitro, in vivo, and in humans. Trilaciclib is currently being tested as a treatment for hormone-dependent breast cancer. The drug works by targeting the microenvironment and inhibiting fibroblast growth factor (FGF) from binding to its receptor on the surface of cells. This leads to cell death through apoptosis and immunogenic cell death, which can be used for the treatment of tumors. Trilaciclib also enhances natural killer cell activity, which may help with cancer patients’ immunity against tumor cells.

Formula: C₂₄H₃₂Cl₂N₈O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 519.47 g/mol

Ref: 3D-CED49597