CAS 1980821-53-1

pan-Raf/RTK inhibitor 1

CAS: 1980821-53-1

Pan-Raf/RTK inhibitor 1 (compound I-16) is a potent pan-Raf inhibitor with IC50 values of 3.49 nM (BRafV600E), 8.86 nM (ARaf), 5.78 nM (BRafWT), and 1.65 nM (CRaf). It exhibits antiproliferative activity against various cancer cell lines and can be utilized in cancer research.

Formula: C₂₉H₂₈F₃N₇O₃

Color and Shape: Solid

Molecular weight: 579.573

Ref: TM-T204155