CAS 198470-85-8
:Parecoxib sodium
Description:
Parecoxib sodium is a non-steroidal anti-inflammatory drug (NSAID) that belongs to the class of selective cyclooxygenase-2 (COX-2) inhibitors. It is primarily used for the management of postoperative pain and is administered parenterally. As a prodrug, parecoxib is converted in the body to its active form, valdecoxib, which exerts its analgesic and anti-inflammatory effects by selectively inhibiting COX-2, thereby reducing the production of prostaglandins involved in pain and inflammation. Parecoxib sodium is characterized by its sodium salt form, which enhances its solubility in aqueous solutions, making it suitable for intravenous administration. The substance is typically presented as a white to off-white crystalline powder and is stable under normal conditions. Its pharmacokinetics include rapid absorption and metabolism, with a relatively short half-life. While effective for pain relief, parecoxib sodium, like other NSAIDs, may carry risks of cardiovascular and gastrointestinal side effects, necessitating careful patient selection and monitoring during use.
Formula:C19H17N2NaO4S
InChI:InChI=1/C19H18N2O4S.Na/c1-3-17(22)21-26(23,24)16-11-9-14(10-12-16)18-13(2)25-20-19(18)15-7-5-4-6-8-15;/h4-12H,3H2,1-2H3,(H,21,22);/q;+1/p-1
InChI key:InChIKey=IMBMHWVEMVJSIQ-UHFFFAOYSA-N
SMILES:CC1=C(C(=NO1)C2=CC=CC=C2)C3=CC=C(S(NC(CC)=O)(=O)=O)C=C3.[Na]
Synonyms:- Dynastat
- N-[4-(5-Methyl-3-Phenylisoxazol-4-YL)Phenylsulfonyl]Propionamide, sodium salt
- Propanamide, N-[[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-, sodium salt
- Propanamide, N-[[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-, sodium salt (1:1)
- Rayzon
- Sc 69124A
- Parecoxib sodium
- （Intermediate in China ONLY）
- N-[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonyl]propanamide sodium hydride
- Parecoxib sodiuM sal
- sodium ((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)(propionyl)amide
- PARECOXIB SODIUM USP/EP/BP
- N-[[4-(5-Methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]propanamide Sodium Salt（Parecoxib Sodium）
- parexib sodium
- Parecoxib Sodium Impurity
- Parecoxib Impurity 64
- sodium ((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonysodium ((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl) (propionyl)amidel) (propionyl)amide
- Parecoxib Impurity 22 Sodium Salt
- Parecoxib sodiuM salt
- Parecoxib CRS
- Parecoxib sodiuM cloth
- Parecoxib-011-Na
- See more synonyms
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Found 13 products.
Propanamide, N-[[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-, sodium salt (1:1)
CAS:Formula:C19H17N2NaO4SPurity:98%Color and Shape:SolidMolecular weight:392.4040Ref: IN-DA002BIZ
1g576.00€5gTo inquire5mg56.00€10mg57.00€25mg55.00€50mg67.00€100mg120.00€250mg162.00€Parecoxib Sodium Salt
CAS:Formula:C19H17N2O4S·NaColor and Shape:White To Off-White SolidMolecular weight:369.42 22.99Parecoxib Sodium
CAS:Formula:C19H17N2NaO4SPurity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:392.40Parecoxib Sodium
CAS:Controlled ProductFormula:C19H17N2O4S·NaColor and Shape:NeatMolecular weight:392.40Parecoxib sodium
CAS:Parecoxib: COX2 inhibitor, treats short-term postoperative pain, water-soluble, injectable, valdecoxib prodrug, less GI toxicity than ketorolac.Formula:C19H18N2NaO4SPurity:98%Color and Shape:SolidMolecular weight:393.41Parecoxib Sodium
CAS:Controlled ProductApplications Anti-inflammatory, analgesic.
References Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Polascheck, N., et al.: Exper. Neurol., 224, 219 (2010), Gudbjornsson, B., et al.: Eur. J. Clin. Pharmacol., 66, 619 (2010),Formula:C19H17N2O4S·NaColor and Shape:WhiteMolecular weight:392.4Parecoxib-d5 Sodium
CAS:Controlled ProductApplications Labelled Parecoxib (P193275). Anti-inflammatory, analgesic.
References Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Polascheck, N., et al.: Exper. Neurol., 224, 219 (2010), Gudbjornsson, B., et al.: Eur. J. Clin. Pharmacol., 66, 619 (2010),Formula:C19H12D5N2NaO4SColor and Shape:NeatMolecular weight:397.43Parecoxib sodium salt - Bio-X ™
CAS:Controlled ProductParecoxib is a COX-2 inhibitor and belongs to the group of pharmacological agents. It is a prodrug of valdecoxib that is used for the treatment of osteoarthritis and rheumatoid arthritis, as well as other conditions where the reduction in pain and inflammation are desired.
Formula:C19H17N2NaO4SPurity:Min. 95%Color and Shape:PowderMolecular weight:392.41 g/molParecoxib sodium
CAS:Controlled ProductCOX-2 inhibitor; prodrug of valdecoxib
Formula:C19H18N2O4S·NaPurity:Min. 95%Color and Shape:White PowderMolecular weight:394.42 g/mol
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