CAS 1985605-59-1

Baloxavir

Description:

Baloxavir marboxil is an antiviral medication primarily used for the treatment of influenza. It functions as a polymerase acidic endonuclease inhibitor, disrupting the viral replication process by preventing the cap-dependent transcription of viral RNA. This mechanism of action distinguishes it from other antiviral agents, such as neuraminidase inhibitors. Baloxavir is administered orally and is notable for its single-dose regimen, which enhances patient compliance. The substance is characterized by its relatively low molecular weight and specific structural features that contribute to its efficacy against various strains of the influenza virus, including those resistant to other antiviral treatments. Baloxavir marboxil is prodrug, meaning it is metabolized in the body to its active form, which is responsible for its antiviral activity. Its safety profile includes common side effects such as headache and gastrointestinal disturbances, but it is generally well-tolerated. The development of baloxavir represents a significant advancement in influenza treatment, particularly in the context of emerging viral resistance.

Baloxavir

CAS: 1985605-59-1

Formula: C₂₄H₁₉F₂N₃O₄S

Purity: 97%

Color and Shape: Solid

Molecular weight: 483.4872

Ref: IN-DA01EORA

Baloxavir

CAS: 1985605-59-1

Baloxavir (S-033447) is a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit.

Formula: C₂₄H₁₉F₂N₃O₄S

Purity: 99.26% - 99.87%

Color and Shape: Solid

Molecular weight: 483.49

Ref: TM-T14495

Baloxavir

CAS: 1985605-59-1

Baloxavir

Purity: ≥98%

Molecular weight: 483.49g/mol

Ref: 54-BUP15270

Baloxavir

CAS: 1985605-59-1

Formula: C₂₄H₁₉F₂N₃O₄S

Color and Shape: Pale Pink Solid

Molecular weight: 483.49

Ref: 4Z-B-192003

(R)-12-((S)-7,8-Difluoro-6,11-Dihydrodibenzo[B,E]Thiepin-11-Yl)-7-Hydroxy-3,4,12,12A-Tetrahydro-1H-[1,4]Oxazino[3,4-C]Pyrido[2,1-F][1,2,4]Triazine-6,8-Dione

CAS: 1985605-59-1

(R)-12-((S)-7,8-Difluoro-6,11-Dihydrodibenzo[B,E]Thiepin-11-Yl)-7-Hydroxy-3,4,12,12A-Tetrahydro-1H-[1,4]Oxazino[3,4-C]Pyrido[2,1-F][1,2,4]Triazine-6,8-Dione

Purity: 97%

Molecular weight: 483.49g/mol

Ref: 54-PC108947

Baloxavir

CAS: 1985605-59-1

Formula: C₂₄H₁₉F₂N₃O₄S

Purity: ≥ 98.0%

Color and Shape: White to yellow solid

Molecular weight: 483.49

Ref: 7W-GP6049

Baloxavir-d5

CAS: 1985605-59-1

Formula: C₂₄H₁₄D₅F₂N₃O₄S

Color and Shape: White To Off-White Solid

Molecular weight: 488.52

Ref: 4Z-B-192005

Baloxavir-d3

CAS: 1985605-59-1

Formula: C₂₄H₁₆D₃F₂N₃O₄S

Molecular weight: 486.51

Ref: 4Z-B-192004

BALOXAVIR

CAS: 1985605-59-1

Purity: 97%

Molecular weight: 483.4899902

Ref: 10-F845040

Baloxavir-d4

Controlled Product

CAS: 1985605-59-1

Formula: C₂₅D₄H₁₆F₂N₂O₄S

Color and Shape: Neat

Molecular weight: 486.524

Ref: TR-B838753

Baloxavir

CAS: 1985605-59-1

Baloxavir is an antiviral drug that belongs to the class of endonuclease inhibitors. The compound has been shown to inhibit the activity of influenza virus polymerase, which is necessary for viral replication. Baloxavir is a prodrug that is activated by esterases in the gastrointestinal tract and becomes baloxavir marboxil after hydrolysis. It has demonstrated antiviral activity against influenza A and B viruses with a mechanism of action distinct from oseltamivir, which inhibits the neuraminidase enzyme on the surface of influenza viruses.

Formula: C₂₆H₂₁F₂NO₄S

Purity: Min. 95%

Molecular weight: 481.51 g/mol

Ref: 3D-KED60559

Baloxavir

Controlled Product

CAS: 1985605-59-1

Formula: C₂₄H₁₉F₂N₃O₄S

Color and Shape: Neat

Molecular weight: 483.487

Ref: TR-B838750