CAS 198572-71-3

N-(TERT-BUTOXYCARBONYL)-2-NITROBENZENESULFONAMIDE

Description:

N-(tert-Butoxycarbonyl)-2-nitrobenzenesulfonamide is a chemical compound characterized by its sulfonamide functional group, which is linked to a nitro-substituted aromatic ring. The tert-butoxycarbonyl (Boc) group serves as a protective group for amines, enhancing the compound's stability and solubility in organic solvents. This compound typically appears as a solid and is often used in organic synthesis, particularly in the preparation of pharmaceuticals and biologically active molecules. Its structure includes a nitro group, which can influence its reactivity and polarity, making it useful in various chemical reactions. The sulfonamide moiety contributes to its potential biological activity, as sulfonamides are known for their antibacterial properties. The compound's CAS number, 198572-71-3, allows for its identification in chemical databases and literature. Overall, N-(tert-butoxycarbonyl)-2-nitrobenzenesulfonamide is a versatile intermediate in synthetic chemistry, valued for its functional groups that facilitate further chemical transformations.

Formula: C₁₁H₁₄N₂O₆S

InChI: InChI=1/C11H14N2O6S/c1-11(2,3)19-10(14)12-20(17,18)9-7-5-4-6-8(9)13(15)16/h4-7H,1-3H3,(H,12,14)

SMILES: CC(C)(C)OC(=NS(=O)(=O)c1ccccc1N(=O)=O)O

Synonyms:

• N-Boc-O-Nitrobenzenesulfonamide
• N-Boc-2-Nitrobenzenesulfonamide
• Tert-Butyl [(2-Nitrophenyl)Sulfonyl]Carbamate

N-(tert-Butoxycarbonyl)-2-nitrobenzenesulfonamide

CAS: 198572-71-3

Formula: C₁₁H₁₄N₂O₆S

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 302.30

Ref: 3B-B2303

Carbamic acid, N-[(2-nitrophenyl)sulfonyl]-, 1,1-dimethylethyl ester

CAS: 198572-71-3

Formula: C₁₁H₁₄N₂O₆S

Purity: 96%

Color and Shape: Solid

Molecular weight: 302.3037

Ref: IN-DA002BMC

tert-Butyl ((2-nitrophenyl)sulfonyl)carbamate

CAS: 198572-71-3

tert-Butyl ((2-nitrophenyl)sulfonyl)carbamate

Purity: 99%

Molecular weight: 302.31g/mol

Ref: 54-OR74717

N-(tert-Butoxycarbonyl)-2-nitrobenzenesulfonamide

CAS: 198572-71-3

N-(tert-Butoxycarbonyl)-2-nitrobenzenesulfonamide is a macrocyclization agent that initiates and controls cyclization by alkylation of amines. The intramolecular nitroarene macrocyclization is stereoselectively controlled through diastereoselective synthesis. Nitrogen atoms in the nitroarene are activated with tert-butoxycarbonyl chloride to form an intermediate, which is then reacted with amines to form the macrocycle. This process is stereochemically mediated and produces a single diastereomer of the product.

Formula: C₁₁H₁₄N₂O₆S

Purity: Min. 95%

Molecular weight: 302.3 g/mol

Ref: 3D-FB59870

tert-Butyl (2-nitrophenyl)sulfonylcarbamate

CAS: 198572-71-3

Formula: C₁₁H₁₄N₂O₆S

Purity: 96%

Color and Shape: Solid

Molecular weight: 302.3

Ref: 10-F463135