CAS 19906-72-0

bakkenolide A

Description:

Bakkenolide A is a natural compound classified as a sesquiterpene lactone, primarily derived from the plant species *Artemisia bakkeana*. It is characterized by its unique chemical structure, which includes a lactone ring and multiple chiral centers, contributing to its biological activity. This compound exhibits various pharmacological properties, including anti-inflammatory, anti-cancer, and antimicrobial effects, making it of interest in medicinal chemistry and natural product research. Bakkenolide A is typically studied for its potential therapeutic applications, particularly in the context of traditional medicine. Its solubility and stability can vary depending on the solvent and environmental conditions, which are important factors to consider in experimental settings. Additionally, the compound's interactions with biological systems are an area of ongoing research, as understanding these interactions can lead to the development of novel therapeutic agents. Overall, bakkenolide A represents a significant example of the bioactive compounds found in nature, highlighting the importance of plant-derived substances in drug discovery.

Formula: C₁₅H₂₂O₂

InChI: InChI=1/C15H22O2/c1-10-5-4-6-12-7-15(9-14(10,12)3)11(2)8-17-13(15)16/h10,12H,2,4-9H2,1,3H3/t10-,12+,14+,15+/m0/s1

InChI key: InChIKey=OVXAYHNZXBOVPV-QMGNLALYSA-N

SMILES: C=C1[C@@]2(C[C@@]3(C)[C@@](C2)(CCC[C@@H]3C)[H])C(=O)OC1

Synonyms:

• (2′R,3′aR,4′S,7′aR)-Decahydro-3′a,4′-dimethyl-4-methylenespiro[furan-3(2H),2′-[2H]inden]-2-one
• (3R,3a'R,4'S,7a'R)-3a',4'-dimethyl-4-methylidenedecahydrospiro[furan-3,2'-inden]-2-one
• 3A',4'-Dimethyl-4-Methylidenedecahydrospiro[Furan-3,2'-Inden]-2-One
• Bakkenolid A
• Fukinanolid
• Fukinanolide
• Nsc 292655
• Spiro(furan-3(2H),2'-(2H)inden)-2-one, decahydro-3'a,4'-dimethyl-4-methylene-, (2'R-(2'alpha,3'aalpha,4'alpha,7'aalpha))- (9CI)
• Spiro(furan-3(2H),2'-indan)-2-one, 3'a,4,4',5,5',6',7',7'abeta-octahydro-3'abeta,4'beta-dimethyl-4-methylene-, (2'R)- (8CI)
• Spiro[furan-3(2H),2′-[2H]inden]-2-one, decahydro-3′a,4′-dimethyl-4-methylene-, (2′R,3′aR,4′S,7′aR)-
• Spiro[furan-3(2H),2′-[2H]inden]-2-one, decahydro-3′a,4′-dimethyl-4-methylene-, [2′R-(2′α,3′aα,4′α,7′aα)]-
• Spiro[furan-3(2H),2′-indan]-2-one, 3′a,4,4′,5,5′,6′,7′,7′aβ-octahydro-3′aβ,4′β-dimethyl-4-methylene-, (2′R)-
• ( )-Bakkenolide A
• Bakkenolide A
• (3R)-1',3',3'a,4,4',5,5',6',7',7'aβ-Decahydro-3'aβ,4'β-dimethyl-4-methylenespiro[furan-3(2H),2'-[2H]inden]-2-one
• (2'R,3'aR,4'S,7'aR)-Decahydro-3'a,4'-dimethyl-4-methylenespiro[furan-3(2H),2'-[2H]inden]-2-one
• Spiro[furan-3(2H),2'-[2H]inden]-2-one, decahydro-3'a,4'-dimethyl-4-methylene-, (2'R,3'aR,4'S,7'aR)-
• (2R,3aR,7S,7aR)-7,7a-dimethyl-4'-methylidenespiro[3,3a,4,5,6,7-hexahydro-1H-indene-2,3'-oxolane]-2'-one

Bakkenolide A

CAS: 19906-72-0

Bakkenolide A has antifeedant and growth inhibitory effects on neonate variegated cutworms, it inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related

Formula: C₁₅H₂₂O₂

Color and Shape: Solid

Molecular weight: 234.33

Ref: TM-T2S0606

Bakkenolide A

CAS: 19906-72-0

Formula: C₁₅H₂₂O₂

Purity: 95%~99%

Molecular weight: 234.339

Ref: BP-BP0234

Bakkenolide A

CAS: 19906-72-0

Bakkenolide A is a sesquiterpene lactone, which is a type of bioactive compound derived from the plant species Petasites, commonly found in traditional medicinal herbs. It is characterized by its unique structural configuration that contributes to its potent biological activity. The primary mode of action associated with Bakkenolide A involves the inhibition of pro-inflammatory cytokines and signaling pathways such as NF-κB, which play a crucial role in the inflammatory response.

Formula: C₁₅H₂₂O₂

Purity: Min. 95%

Molecular weight: 234.33 g/mol

Ref: 3D-UAA90672