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CAS 199113-98-9

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Balaglitazone

Description:
Balaglitazone is a synthetic compound belonging to the thiazolidinedione class of drugs, primarily used in the management of type 2 diabetes mellitus. It acts as a selective agonist for the peroxisome proliferator-activated receptor gamma (PPAR-γ), which plays a crucial role in glucose and lipid metabolism. The compound is characterized by its ability to enhance insulin sensitivity, thereby improving glycemic control in diabetic patients. Balaglitazone has been studied for its potential to reduce insulin resistance and promote adipocyte differentiation. Its chemical structure includes a thiazolidinedione moiety, which is essential for its biological activity. The pharmacokinetics of Balaglitazone involve absorption, distribution, metabolism, and excretion processes that are typical for oral antidiabetic agents. While it shows promise in clinical settings, the safety profile and long-term effects of Balaglitazone require thorough evaluation through clinical trials. Overall, Balaglitazone represents a significant advancement in diabetes treatment, focusing on metabolic regulation and insulin action.
Formula:C20H17N3O4S
InChI:InChI=1S/C20H17N3O4S/c1-23-17(21-15-5-3-2-4-14(15)19(23)25)11-27-13-8-6-12(7-9-13)10-16-18(24)22-20(26)28-16/h2-9,16H,10-11H2,1H3,(H,22,24,26)
InChI key:IETKPTYAGKZLKY-UHFFFAOYSA-N
SMILES:CN1C(=NC2=CC=CC=C2C1=O)COC3=CC=C(C=C3)CC4C(=O)NC(=O)S4
Synonyms:
  • 2,4-Thiazolidinedione,5-[[4-[(3,4-dihydro-3-methyl-4-oxo-2-quinazolinyl) methoxy]phenyl]methyl]-
Found 5 products.