CAS 19983-44-9

Stattic

Description:

Stattic, with the CAS number 19983-44-9, is a chemical compound known for its role as a selective inhibitor of the protein kinase activity of the enzyme Src. It is primarily utilized in biochemical research to study cellular signaling pathways and the effects of Src inhibition on various biological processes. Stattic is characterized by its ability to disrupt the Src signaling pathway, which is implicated in numerous cellular functions, including proliferation, survival, and migration. The compound is typically used in laboratory settings, and its effectiveness can vary based on the specific cell types and experimental conditions. As with many chemical substances, safety precautions should be observed when handling Stattic, including the use of appropriate personal protective equipment and adherence to safety data sheet guidelines. Its research applications contribute to a better understanding of cancer biology and potential therapeutic strategies targeting Src-related pathways.

Formula: C₈H₅NO₄S

InChI: InChI=1S/C8H5NO4S/c10-9(11)7-2-1-6-3-4-14(12,13)8(6)5-7/h1-5H

InChI key: InChIKey=ZRRGOUHITGRLBA-UHFFFAOYSA-N

SMILES: O=S1(=O)C=2C(C=C1)=CC=C(N(=O)=O)C2

Synonyms:

• 6-Nitro-1-Benzothiophene 1,1-Dioxide
• 6-Nitrobenzo[b]thiophene 1,1-dioxide
• Benzo[b]thiophene, 6-nitro-, 1,1-dioxide
• Stattic

1,1-Dioxide-6-nitro-benzo[b]thiophene

CAS: 19983-44-9

Formula: C₈H₅NO₄S

Purity: 95%

Color and Shape: Solid

Molecular weight: 211.1946

Ref: IN-DA002CE6

Stattic

CAS: 19983-44-9

Stattic

Purity: ≥98%

Molecular weight: 211.19g/mol

Ref: 54-BUP15393

6-Nitrobenzo[b]thiophene 1,1-dioxide

CAS: 19983-44-9

6-Nitrobenzo[b]thiophene 1,1-dioxide

Formula: C₈H₅NO₄S

Purity: 95%

Color and Shape: cream powder

Molecular weight: 211.19g/mol

Ref: 54-OR26006

Stattic

CAS: 19983-44-9

Formula: C₈H₅NO₄S

Molecular weight: 211.19

Ref: 7W-GK3981

Stattic

CAS: 19983-44-9

Stattic (STAT3 Inhibitor V) is a STAT3 inhibitor (IC50=5.1 μM) that selectively inhibits STAT3 activation, dimerization, and nuclear translocation.

Formula: C₈H₅NO₄S

Purity: 98.32% - 99.76%

Color and Shape: Solid

Molecular weight: 211.19

Ref: TM-T6308

6-Nitrobenzo[b]thiophene 1,1-dioxide

CAS: 19983-44-9

Formula: C₈H₅NO₄S

Purity: 95%+

Color and Shape: Liquid, No data available.

Molecular weight: 211.19

Ref: 10-F322052

Stattic

CAS: 19983-44-9

Stattic is a small molecule that binds to DNA and prevents the polymerase chain reaction (PCR). Stattic has been shown to have synergistic effects with radiation in the treatment of cancer. Stattic also has pro-apoptotic activity, which leads to the activation of caspases, which are enzymes responsible for apoptosis. Stattic inhibits hyperproliferative disease by binding to DNA and preventing transcription, which prevents protein synthesis from occurring. This drug also has anti-cancer properties due to its ability to bind to DNA and inhibit cellular transformation.

Formula: C₈H₅NO₄S

Purity: Min. 95%

Molecular weight: 211.19 g/mol

Ref: 3D-UAA98344