CAS 20054-45-9

2-mercapto-N-methylbenzamide

Description:

2-Mercapto-N-methylbenzamide, with the CAS number 20054-45-9, is an organic compound characterized by the presence of both a thiol (-SH) group and an amide functional group. This compound features a benzene ring substituted with a methyl group and a mercapto group, which contributes to its reactivity and potential applications in various chemical processes. The thiol group imparts properties such as nucleophilicity and the ability to form disulfide bonds, making it useful in biochemical applications, including protein modification and synthesis. The amide functionality enhances the compound's solubility in polar solvents and can influence its biological activity. 2-Mercapto-N-methylbenzamide may exhibit antioxidant properties due to the presence of the thiol group, and it can participate in redox reactions. Additionally, its structural characteristics suggest potential uses in pharmaceuticals, agrochemicals, and materials science. As with many thiol-containing compounds, it may have a distinct odor and should be handled with care due to its potential reactivity and toxicity.

Formula: C₈H₉NOS

InChI: InChI=1S/C8H9NOS/c1-9-8(10)6-4-2-3-5-7(6)11/h2-5,11H,1H3,(H,9,10)

InChI key: VIFOAZNEQRHREM-UHFFFAOYSA-N

SMILES: CNC(=O)C1=CC=CC=C1S

Synonyms:

• 2-mercapto-N-methyl-Benzamide
• 2-Merceapto-N-methylbenzamine
• N-methyl-2-sulfanylbenzamide

Axitinib Related Compound B

CAS: 20054-45-9

Other aromatic organo-sulfur compounds (excluding pesticides)

Formula: C₈H₉NOS

Color and Shape: White Off-White Powder

Molecular weight: 167.04049

Ref: 45-1045512

2-Mercapto-N-methylbenzamide

CAS: 20054-45-9

Formula: C₈H₉NOS

Purity: 95%

Color and Shape: Solid

Molecular weight: 167.2282

Ref: IN-DA002CU8

Axitinib Impurity 47

CAS: 20054-45-9

Formula: C₈H₉NOS

Molecular weight: 167.23

Ref: 4Z-A-188050

2-Mercapto-N-methylbenzamide

CAS: 20054-45-9

2-Mercapto-N-methylbenzamide

Formula: C₈H₉NOS

Purity: 98%

Molecular weight: 167.22816

Ref: 54-OR54613

2-Mercapto-N-methylbenzamide

CAS: 20054-45-9

Formula: C₈H₉NOS

Purity: ≥ 95.0%

Color and Shape: White to off-white solid

Molecular weight: 167.231

Ref: 7W-GX3406

2-Mercapto-N-methyl-benzamide

Controlled Product

CAS: 20054-45-9

Stability Air Sensitive
Applications 2-Mercapto-N-methyl-benzamide is an intermediate used to prepare axitinib (A794650) which is a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.
References Wasser, K., et al.: Eur. Radiol., 13, 80 (2003), Park, J., et al.: Clin. Cancer Res., 8, 1172 (2002), Bergers, G., et al.: J. Clin. Invest., 111, 1287 (2003),

Formula: C₈H₉NOS

Color and Shape: Neat

Molecular weight: 167.228

Ref: TR-M225230

2-Mercapto-N-methylbenzamide

CAS: 20054-45-9

2-Mercapto-N-methylbenzamide

Formula: C₈H₉NOS

Purity: 98%

Molecular weight: 167.23

Ref: IN-DG168641

N-METHYL-2-SULFANYLBENZAMIDE

CAS: 20054-45-9

Formula: C₈H₉NOS

Purity: 95%

Molecular weight: 167.23

Ref: 10-F500467

2-Mercapto-N-methyl benzamide

CAS: 20054-45-9

Formula: C₈H₉NOS

Molecular weight: 167.23

Ref: ST-EA-CP-A34022

2-Mercapto-N-methylbenzamide

CAS: 20054-45-9

2-Mercapto-N-methylbenzamide is a synthetic compound that has been shown to have inhibitory activities against activated brain cells and cell lines. This drug has been used in the synthesis of axitinib, a cancer drug that inhibits cellular growth. 2-Mercapto-N-methylbenzamide is also used as a preservative in cosmetics and can be found in carbonated drinks and foods. It has been shown to inhibit the production of serotonin in microbicidal reactions by inhibiting the enzyme hydroxymethyl transferase, which catalyzes the conversion of 5-hydroxytryptophan to serotonin. It also prevents the reaction products from being formed by reacting with hypoxanthine, xanthine, and phosphoribosyl pyrophosphate (PRPP). 2-Mercapto-N-methylbenzamide also reacts with plasma samples to form ethylmercaptoacetate, which is then oxidized to merc

Formula: C₈H₉NOS

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 167.23 g/mol

Ref: 3D-FM45433