CAS 20069-09-4

Piperlongumine

Description:

Piperlongumine is a natural alkaloid derived from the plant Piper longum, commonly known as long pepper. It is characterized by its unique chemical structure, which includes a piperidine ring and a long carbon chain. This compound has garnered attention for its potential pharmacological properties, including anti-inflammatory, antioxidant, and anticancer activities. Piperlongumine has been shown to induce apoptosis in various cancer cell lines and may enhance the efficacy of certain chemotherapeutic agents. Its mechanism of action is thought to involve the modulation of various signaling pathways, including those related to oxidative stress and cell survival. Additionally, Piperlongumine exhibits low toxicity in normal cells, making it a promising candidate for further research in cancer therapy. The substance is typically studied in the context of its bioactive properties and potential therapeutic applications, although more clinical research is needed to fully understand its efficacy and safety in humans. As with any bioactive compound, proper handling and dosage are essential for safe use.

Formula: C₁₇H₁₉NO₅

InChI: InChI=1S/C17H19NO5/c1-21-13-10-12(11-14(22-2)17(13)23-3)7-8-16(20)18-9-5-4-6-15(18)19/h4,6-8,10-11H,5,9H2,1-3H3/b8-7+

InChI key: InChIKey=VABYUUZNAVQNPG-BQYQJAHWSA-N

SMILES: O(C)C1=C(OC)C(OC)=CC(/C=C/C(=O)N2C(=O)C=CCC2)=C1

Synonyms:

• 2(1H)-Pyridinone, 5,6-dihydro-1-(1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl)-, (E)-
• 2(1H)-Pyridinone, 5,6-dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-
• 2(1H)-Pyridinone, 5,6-dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]-
• 2(1H)-Pyridone, 5,6-dihydro-1-(3,4,5-trimethoxycinnamoyl)-
• 5,6-Dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-2(1H)-pyridinone
• Piperlongumine
• Piperlonguminine
• Piplartin
• Piplartine

Piperlongumine

CAS: 20069-09-4

Formula: C₁₇H₁₉NO₅

Purity: >97.0%(HPLC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 317.34

Ref: 3B-P2361

Piperlongumine

CAS: 20069-09-4

Piperlongumine analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₁₇H₁₉NO₅

Purity: (HPLC) ≥90%

Color and Shape: Powder

Molecular weight: 317.35

Ref: 11-1868

2(1H)-Pyridinone, 5,6-dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-

CAS: 20069-09-4

Formula: C₁₇H₁₉NO₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 317.3365

Ref: IN-DA002CWY

Piperlongumine

CAS: 20069-09-4

Piperlongumine

Purity: ≥95%

Molecular weight: 317.34g/mol

Ref: 54-BUP11196

Piperlongumine

CAS: 20069-09-4

Formula: C₁₇H₁₉NO₅

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 317.341

Ref: BP-BP3320

Piperlongumine

CAS: 20069-09-4

Formula: C₁₇H₁₉NO₅

Molecular weight: 317.34

Ref: 4Z-P-452001

Piperlongumine

CAS: 20069-09-4

Formula: C₁₇H₁₉NO₅

Purity: ≥ 97%

Color and Shape: White to off-white crystalline powder

Molecular weight: 317.34

Ref: 7W-GK8547

Piperlongumine

CAS: 20069-09-4

Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.

Formula: C₁₇H₁₉NO₅

Purity: 97.03% - 99.90%

Color and Shape: Solid

Molecular weight: 317.34

Ref: TM-T6947

Piperlongumine

CAS: 20069-09-4

Piperlongumine

Formula: C₁₇H₁₉NO₅

Purity: By hplc: 98.78% (Typical Value in Batch COA)

Color and Shape: off-white powder

Molecular weight: 317.34g/mol

Ref: 54-BIDF1035

Piperlongumine

CAS: 20069-09-4

Lactams

Formula: C₁₇H₁₉NO₅

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 317.34

Ref: 5G-86198

Piperlongumine

Controlled Product

CAS: 20069-09-4

Stability Light Sensitive
Applications Piperlongumine (PL), a new alkaloid abundantly present in Piper longum fruits strongly inhibited platelet cell aggregation. It may have anti-cancer properties. It selectively targets and kills cancer cells but leaving normal cells unharmed.
References Beretz, A., et al.: Planta Med., 57, 68 (1991), Lee, S., et al.: J. Microbiol. Biotechnol., 12, 679 (2002), Lee, K., et al.: Pharmacol. Res., 53, 265 (2006),

Formula: C₁₇H₁₉NO₅

Color and Shape: Neat

Molecular weight: 317.34

Ref: TR-P482850

Piperlongumine

CAS: 20069-09-4

Piperlongumine is a naturally occurring alkaloid, which is isolated from the fruit of the Piper longum plant. This compound has shown promise due to its selective cytotoxicity toward cancer cells. Its mode of action involves elevating reactive oxygen species (ROS) levels within cells, leading to oxidative stress that preferentially affects cancerous cells, which exhibit higher basal levels of oxidative stress compared to normal cells.

Formula: C₁₇H₁₉NO₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 317.34 g/mol

Ref: 3D-FP27075

PIPERLONGUMINE

CAS: 20069-09-4

Formula: C₁₇H₁₉NO₅

Purity: 98%

Molecular weight: 317.341

Ref: 10-F302580