CAS 20069-09-4
:Piperlongumine
Description:
Piperlongumine is a natural alkaloid derived from the plant Piper longum, commonly known as long pepper. It is characterized by its unique chemical structure, which includes a piperidine ring and a long carbon chain. This compound has garnered attention for its potential pharmacological properties, including anti-inflammatory, antioxidant, and anticancer activities. Piperlongumine has been shown to induce apoptosis in various cancer cell lines and may enhance the efficacy of certain chemotherapeutic agents. Its mechanism of action is thought to involve the modulation of various signaling pathways, including those related to oxidative stress and cell survival. Additionally, Piperlongumine exhibits low toxicity in normal cells, making it a promising candidate for further research in cancer therapy. The substance is typically studied in the context of its bioactive properties and potential therapeutic applications, although more clinical research is needed to fully understand its efficacy and safety in humans. As with any bioactive compound, proper handling and dosage are essential for safe use.
Formula:C17H19NO5
InChI:InChI=1S/C17H19NO5/c1-21-13-10-12(11-14(22-2)17(13)23-3)7-8-16(20)18-9-5-4-6-15(18)19/h4,6-8,10-11H,5,9H2,1-3H3/b8-7+
InChI key:InChIKey=VABYUUZNAVQNPG-BQYQJAHWSA-N
SMILES:O(C)C1=C(OC)C(OC)=CC(/C=C/C(=O)N2C(=O)C=CCC2)=C1
Synonyms:- 2(1H)-Pyridinone, 5,6-dihydro-1-(1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl)-, (E)-
- 2(1H)-Pyridinone, 5,6-dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-
- 2(1H)-Pyridinone, 5,6-dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]-
- 2(1H)-Pyridone, 5,6-dihydro-1-(3,4,5-trimethoxycinnamoyl)-
- 5,6-Dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-2(1H)-pyridinone
- Piperlongumine
- Piperlonguminine
- Piplartin
- Piplartine
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Piperlongumine
CAS:Formula:C17H19NO5Purity:>97.0%(HPLC)Color and Shape:White to Orange to Green powder to crystalMolecular weight:317.34Piperlongumine
CAS:PiperlongumineFormula:C17H19NO5Purity:By hplc: 98.78% (Typical Value in Batch COA)Color and Shape:SolidMolecular weight:317.33646Piperlongumine
CAS:PiperlongumineFormula:C17H19NO5Purity:99.5%Color and Shape:SolidMolecular weight:317.34Piperlongumine
CAS:Piperlongumine analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.Formula:C17H19NO5Purity:(HPLC) ≥90%Color and Shape:PowderMolecular weight:317.35Piperlongumine
CAS:Controlled ProductStability Light Sensitive
Applications Piperlongumine (PL), a new alkaloid abundantly present in Piper longum fruits strongly inhibited platelet cell aggregation. It may have anti-cancer properties. It selectively targets and kills cancer cells but leaving normal cells unharmed.
References Beretz, A., et al.: Planta Med., 57, 68 (1991), Lee, S., et al.: J. Microbiol. Biotechnol., 12, 679 (2002), Lee, K., et al.: Pharmacol. Res., 53, 265 (2006),Formula:C17H19NO5Color and Shape:NeatMolecular weight:317.34Piperlongumine
CAS:Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.Formula:C17H19NO5Purity:97.03% - 99.98%Color and Shape:Green SolidMolecular weight:317.34Piperlongumine
CAS:Formula:C17H19NO5Purity:≥ 97%Color and Shape:White to off-white crystalline powderMolecular weight:317.34Piperlongumine
CAS:LactamsFormula:C17H19NO5Purity:≥ 90.0 % (HPLC)Color and Shape:PowderMolecular weight:317.34(E)-1-(3-(3,4,5-Trimethoxyphenyl)acryloyl)-5,6-dihydropyridin-2(1H)-one
CAS:(E)-1-(3-(3,4,5-Trimethoxyphenyl)acryloyl)-5,6-dihydropyridin-2(1H)-oneFormula:C17H19NO5Purity:98%Molecular weight:317.34Piperlongumine
CAS:Piperlongumine is a naturally occurring alkaloid, which is isolated from the fruit of the Piper longum plant. This compound has shown promise due to its selective cytotoxicity toward cancer cells. Its mode of action involves elevating reactive oxygen species (ROS) levels within cells, leading to oxidative stress that preferentially affects cancerous cells, which exhibit higher basal levels of oxidative stress compared to normal cells.Formula:C17H19NO5Purity:Min. 95%Color and Shape:PowderMolecular weight:317.34 g/mol
