CAS 2009-64-5

Neopterin

Description:

Neopterin is a pteridine derivative that serves as a biomarker for immune system activation. It is produced by macrophages upon stimulation by interferon-gamma, making it significant in clinical diagnostics, particularly in infectious diseases and immune disorders. Neopterin is characterized by its yellow crystalline appearance and is soluble in water and alcohol, which facilitates its detection in biological fluids. The substance has a molecular formula of C13H13N5O3 and a molecular weight that reflects its complex structure, which includes a bicyclic pteridine ring. Neopterin levels can be measured in serum, urine, and cerebrospinal fluid, and elevated concentrations are often associated with various pathological conditions, including viral infections, autoimmune diseases, and certain cancers. Its role as a marker for immune response has made it a subject of interest in both research and clinical settings, providing insights into the status of the immune system and potential disease progression.

Formula: C₉H₁₁N₅O₄

InChI: InChI=1/C9H11N5O4/c10-9-13-7-5(8(18)14-9)12-3(1-11-7)6(17)4(16)2-15/h1,4,6,15-17H,2H2,(H3,10,11,13,14,18)/t4-,6?/m1/s1

InChI key: InChIKey=BMQYVXCPAOLZOK-XINAWCOVSA-N

SMILES: O=C1C=2C(NC=C([C@@H]([C@@H](CO)O)O)N2)=NC(N)=N1

Synonyms:

• 1,2,3-Propanetriol, 1-(2-amino-4-hydroxy-6-pteridinyl)-, <span class="text-smallcaps">D</span>-erythro-
• 1,2,3-Propanetriol, 1-(2-amino-4-hydroxy-6-pteridinyl)-, D-erythro-
• 2-Amino-4-hydroxy-6-(1,2,3-trihydroxypropyl)pteridine
• 2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)-4(8H)-pteridone
• 2-Amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-4(3H)-pteridinone
• 2-amino-6-(1,2,3-trihydroxypropyl)pteridin-4(1H)-one
• 2-amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]pteridin-4(1H)-one
• 4(1H)-Pteridinone, 2-amino-6-(1,2,3-trihydroxypropyl)-, [S-(R*,S*)]-
• 4(1H)-Pteridinone, 2-amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-
• 4(3H)-Pteridinone, 2-amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-
• 6-(<span class="text-smallcaps">D</span>-erythro-1,2,3-Trihydroxypropyl)pterin
• 6-(D-erythro-1,2,3-Trihydroxypropyl)pterin
• 6-<span class="text-smallcaps">D</span>-erythro-Neopterin
• 6-D-erythro-Neopterin
• <span class="text-smallcaps">D</span>-(+)-Neopterin
• <span class="text-smallcaps">D</span>-erythro-Neopterin
• D-(+)-Neopterin
• D-erythro-Neopterin
• Neopterin
• Neopterin D-erythro-form
• [S-(R*,S*)]-2-Amino-6-(1,2,3-trihydroxypropyl)-1H-pteridin-4-on
• [S-(R*,S*)]-2-amino-6-(1,2,3-trihidroxipropil)-1H-pteridin-4-ona
• [S-(R*,S*)]-2-amino-6-(1,2,3-trihydroxypropyl)-1H-pteridine-4-one
• (S-(R*,S*))-2-Amino-6-(1,2,3-trihydroxypropyl)-1H-pteridin-4-one
• 2-Amino-6-[(1R,2S)-1,2,3-trihydroxypropyl]pteridin-4(1H)-one
• D(+)-Neopterin, 99% 10MG
• D-erythro-Form
• D(+)-Neopterin,99%
• D-(PLUS)-NEOPTERINE
• D-(+)-Neopterin >=97.5% (suM of enantioMers, HPLC)
• 1-(2-amino-4-hydroxy-pteridin-6-yl)propane-1,2,3-triol
• D(+)-6-(ERYTHRO-1,2,3-TRIHYDROXYPROPYL)PTERIN

Neopterin

CAS: 2009-64-5

Neopterin

Formula: C₉H₁₁N₅O₄

Purity: ≥98%

Molecular weight: 253.21

Ref: 54-BUP06938

2-Amino-6-((1S,2R)-1,2,3-Trihydroxypropyl)Pteridin-4(3H)-One

CAS: 2009-64-5

2-Amino-6-((1S,2R)-1,2,3-Trihydroxypropyl)Pteridin-4(3H)-One

Formula: C₉H₁₁N₅O₄

Purity: 97%

Molecular weight: 253.21

Ref: 54-OR1024165

2-amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-4(3H)-Pteridinone

CAS: 2009-64-5

Formula: C₉H₁₁N₅O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 253.2147

Ref: IN-DA003P7R

D-Neopterin

CAS: 2009-64-5

Formula: C₉H₁₁N₅O₄

Molecular weight: 253.22

Ref: 4Z-N-100101

Neopterin

CAS: 2009-64-5

2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)pteridin-4(3H)-one

Formula: C₉H₁₁N₅O₄

Purity: 97%

Molecular weight: 253.21

Ref: IN-DG123254

D-Neopterin

Controlled Product

CAS: 2009-64-5

Stability Hygroscopic
Applications Precursor in the biosynthesis of Biopterin. First isolated from the pupae of bees.
References Kobashi, I., et al.: Agric. Biol. Chem., 35, 47 (1971), Fukushima, S., et al.: J. Biol. Chem., 247, 4549 (1972),

Formula: C₉H₁₁N₅O₄

Color and Shape: Neat

Molecular weight: 253.21

Ref: TR-N390005

D-Neopterin Hydrochloride

Controlled Product

CAS: 2009-64-5

Stability Hygroscopic
Applications D-Neopterin Hydrochloride is an intermediate in the synthesis of Dihydroneopterin (D453600). Dihydroneopterin is an impurity of Neopterin (N390005), a precursor in the biosynthesis of Biopterin (B389020).
References Kobashi, I., et al.: Agric. Biol. Chem., 35, 47 (1971); Fukushima, S., et al.: J. Biol. Chem., 247, 4549 (1972)

Formula: C₉H₁₁N₅O₄•(HCl)

Color and Shape: Neat

Molecular weight: 289.67

Ref: TR-D453598

Neopterin

CAS: 2009-64-5

Formula: C₉H₁₁N₅O₄

Molecular weight: 253.22

Ref: ST-EA-CP-S25022

Neopterin

CAS: 2009-64-5

D-(+)-Neopterin (D-(+)-Neopterin) is produced by human monocytes/macrophages upon stimulation with the cytokine interferon-γ.

Formula: C₉H₁₁N₅O₄

Purity: 99.54%

Color and Shape: Solid

Molecular weight: 253.21

Ref: TM-TQ0273