CymitQuimica logo

CAS 201422-03-9

:

PROTEIN KINASE A INHIBITOR 14-22 AMIDE, CELL-PERMEABLE, MYRISTOYLATED

Description:
Protein Kinase A Inhibitor 14-22 Amide, Cell-Permeable, Myristoylated, with the CAS number 201422-03-9, is a synthetic compound designed to inhibit Protein Kinase A (PKA), an important enzyme involved in various cellular signaling pathways. This inhibitor is characterized by its ability to penetrate cell membranes, which is facilitated by its myristoylation, a modification that enhances its lipophilicity and cellular uptake. The compound typically exhibits specificity towards PKA, making it a valuable tool in biochemical research for studying PKA-related signaling pathways and their implications in various physiological and pathological processes. Its amide structure contributes to its stability and interaction with the target enzyme. Researchers utilize this inhibitor to explore the roles of PKA in cellular functions such as metabolism, gene expression, and cell growth, as well as in the development of therapeutic strategies for diseases where PKA signaling is dysregulated. Overall, this compound serves as a critical reagent in the field of molecular biology and pharmacology.
Formula:C53H100N20O12
InChI:InChI=1S/C53H100N20O12/c1-6-8-9-10-11-12-13-14-15-16-17-24-39(76)65-29-40(77)69-35(22-19-26-63-52(58)59)48(83)73-43(33(5)74)50(85)66-30-41(78)68-34(21-18-25-62-51(56)57)46(81)70-36(23-20-27-64-53(60)61)47(82)71-37(28-38(54)75)49(84)67-32(4)45(80)72-42(44(55)79)31(3)7-2/h31-37,42-43,74H,6-30H2,1-5H3,(H2,54,75)(H2,55,79)(H,65,76)(H,66,85)(H,67,84)(H,68,78)(H,69,77)(H,70,81)(H,71,82)(H,72,80)(H,73,83)(H4,56,57,62)(H4,58,59,63)(H4,60,61,64)/t31-,32-,33+,34-,35-,36-,37-,42-,43-/m0/s1
InChI key:GQPQKQWUUHDDIS-JDLJUXOTSA-N
SMILES:CCCCCCCCCCCCCC(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N
Synonyms:
  • PROTEIN KINASE A INHIBITOR 14-22 AMIDE, CELL-PERMEABLE, MYRISTOYLATED
  • 1:PN: US20090092566 SEQID: 1 claimed protein
  • MYRISTOYLATED PKI (14-22) AMIDE
  • PKI 14-22 AMIDE, MYRISTOYLATED
  • PROTEIN KINASE A INHIBITOR 14-22 AMIDE, MYRISTOYLATED
  • 4: PN: WO03080649 SEQID: 4 claimedprotein
  • MYR-GRTGRRNAI-NH2
  • MYRISTOYLATED PROTEIN KINASE A INHIBITOR AMIDE 14-22, CELL-PERMEABLE
  • PKI 14-22 AMIDE, CELL-PERMEABLE
  • L-Isoleucinamide, N-(1-oxotetradecyl)glycyl-L-arginyl-L-threonylglycyl-L-arginyl-L-arginyl-L-asparaginyl-L-alanyl-
Found 3 products.