CAS 202138-50-9
:Tenofovir disoproxil fumarate
Description:
Tenofovir disoproxil fumarate (TDF) is an antiretroviral medication primarily used in the treatment of HIV and chronic hepatitis B infections. It is a prodrug of tenofovir, which means it is metabolized in the body to its active form. TDF is characterized by its ability to inhibit the reverse transcriptase enzyme, thereby preventing viral replication. The compound is a white to off-white crystalline powder, soluble in water, and has a molecular formula that reflects its complex structure, including a fumarate salt. TDF is typically administered orally and is known for its favorable pharmacokinetic profile, allowing for once-daily dosing. It is often used in combination with other antiretroviral agents to enhance efficacy and reduce the risk of resistance. Common side effects may include renal impairment and bone mineral density loss, necessitating monitoring during treatment. Overall, Tenofovir disoproxil fumarate plays a crucial role in modern HIV therapy and is a key component of many treatment regimens.
Formula:C19H30N5O10P
InChI:InChI=1/C19H30N5O10P.C4H4O4/c1-12(2)33-18(25)28-9-31-35(27,32-10-29-19(26)34-13(3)4)11-30-14(5)6-24-8-23-15-16(20)21-7-22-17(15)24;5-3(6)1-2-4(7)8/h7-8,12-14H,6,9-11H2,1-5H3,(H2,20,21,22);1-2H,(H,5,6)(H,7,8)/b;2-1+/t14-;/m1./s1
SMILES:C([C@H](OCP(OCOC(OC(C)C)=O)(OCOC(OC(C)C)=O)=O)C)N1C=2C(N=C1)=C(N)N=CN2.C(=C/C(O)=O)\C(O)=O
Synonyms:- 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, 1,9-bis(1-methylethyl) ester, 5-oxide, (2E)-2-butenedioate (1:1)
- 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, bis(1-methylethyl) ester, 5-oxide, (2E)-2-butenedioate (1:1)
- 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, bis(1-methylethyl) ester, 5-oxide, (R)-, (E)-2-butenedioate (1:1)
- 9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)phosphinyl)methoxy)propyl)adenine fumarate
- Gs 4331-05
- PMPA Prodrug
- Tenofovir DF
- Tenofovir Dipivoxil Fumarate
- Tenofovir Disproxil Fumarate
- Virea
- Viread
- bis({[(1-methylethoxy)carbonyl]oxy}methyl) {[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl}phosphonate (2E)-but-2-enedioate
- Tenofovir disoproxil fumarate
- TENOFOVIR DISOPROXIC
- See more synonyms
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Found 16 products.
TENOFOVIR DISOPROXIL FUMARATE RS
CAS:<p>TENOFOVIR DISOPROXIL FUMARATE RS</p>Formula:C23H34N5O14PMolecular weight:635.5149Tenofovir Disoproxil Fumarate
CAS:<p>Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure</p>Formula:C19H30N5O10P·C4H4O4Color and Shape:White Off-White PowderMolecular weight:635.51(2E)-but-2-enedioic acid bis({[(propan-2-yloxy)carbonyl]oxy}methyl) {[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methanephosphonate
CAS:Formula:C23H34N5O14PPurity:98%Color and Shape:SolidMolecular weight:635.5149Tenofovir Disoproxil Fumarate
CAS:<p>Tenofovir Disoproxil Fumarate</p>Purity:98%Molecular weight:635.52g/molTenofovir Disoproxil Fumarate
CAS:Formula:C19H30N5O10P·C4H4O4Color and Shape:White To Off-White SolidMolecular weight:519.45 116.07Tenofovir Disoproxil Fumarate
CAS:<p>Tenofovir Disoproxil Fumarate</p>Purity:≥98%Molecular weight:635.51g/molTenofovir disoproxil fumarate
CAS:Formula:C23H34N5O14PPurity:≥ 98.0%Color and Shape:White to off-white crystalline powderMolecular weight:635.52Tenofovir Disoproxil Fumarate
CAS:Formula:C19H30N5O10P·C4H4O4Purity:>95.0%(HPLC)(qNMR)Color and Shape:White to Light yellow powder to crystalMolecular weight:635.51Tenofovir Disoproxil Fumarate
CAS:Controlled ProductFormula:C19H30N5O10P·C4H4O4Color and Shape:NeatMolecular weight:635.51Tenofovir Disoproxil Fumarate
CAS:<p>Tenofovir Disoproxil Fumarate (GS-1278 Disoproxil Fumarate) is a pro-drug, a nucleoside reverse transcriptase inhibitor analog of adenosine.</p>Formula:C19H30N5O10P·C4H4O4Purity:98.60% - 99.02%Color and Shape:White To Pink CrystallineMolecular weight:635.51Tenofovir Disoproxil Fumarate
CAS:<p>Applications Acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),<br></p>Formula:C19H30N5O10P·C4H4O4Color and Shape:White To Off-WhiteMolecular weight:635.51Tenofovir disoproxil fumarate - Bio-X ™
CAS:<p>Tenofovir disoproxil is a nucleotide analog reverse transcriptase inhibitor that is used to treat infections such as Hepatitis-B and HIV. This drug is an antiretroviral agent that blocks reverse transcriptase, blocking viral replication.</p>Formula:C23H34N5O14PPurity:Min. 95%Color and Shape:PowderMolecular weight:635.52 g/molTenofovir disoproxil fumarate
CAS:<p>Anti-viral; reverse transcriptase inhibitor</p>Formula:C23H34N5O14PPurity:Min. 97.5 Area-%Color and Shape:White Off-White PowderMolecular weight:635.52 g/molTenofovir Disoproxil-d6 Fumarate
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Isotope labelled Tenofovir Disoproxil Fumarate, an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),<br></p>Formula:C19H24D6N5O10P•C4H4O4Color and Shape:White To Off-WhiteMolecular weight:525.4811607
![(2E)-but-2-enedioic acid bis({[(propan-2-yloxy)carbonyl]oxy}methyl) {[(2R)-1-(6-amino-9H-purin-9-y…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA002836.jpg&w=3840&q=75)
