CAS 202197-26-0: 3-Chloro-4-[(3-fluorophenyl)methoxy]benzenamine

Description: 3-Chloro-4-[(3-fluorophenyl)methoxy]benzenamine, with the CAS number 202197-26-0, is an organic compound characterized by its aromatic structure, which includes a chloro substituent and a methoxy group attached to a phenyl ring. This compound features a primary amine functional group, which contributes to its reactivity and potential applications in various chemical reactions, including nucleophilic substitutions. The presence of the fluorophenyl moiety enhances its lipophilicity and may influence its biological activity, making it of interest in medicinal chemistry. The chlorine atom introduces additional electronic effects, potentially affecting the compound's stability and reactivity. Overall, this compound's unique combination of functional groups and substituents suggests potential utility in pharmaceutical development, particularly in the design of targeted therapies or as intermediates in the synthesis of more complex molecules. Its physical properties, such as solubility and melting point, would depend on the specific interactions of these functional groups in various solvents.

Formula: C₁₃H₁₁ClFNO

InChI: InChI=1S/C13H11ClFNO/c14-12-7-11(16)4-5-13(12)17-8-9-2-1-3-10(15)6-9/h1-7H,8,16H2

InChI key: InChIKey=AYPFEYDGZDPAPE-UHFFFAOYSA-N

SMILES: FC1=CC=CC(=C1)COC2=CC=C(N)C=C2Cl

Synonyms:

• 3-Chloro-4-(3-fluoro-benzyloxy)-phenylamine
• 3-Chloro-4-(3-fluorobenzyloxy)-aniline
• 3-Chloro-4-[(3-fluorobenzyl)oxy]aniline
• 3-Chloro-4-[(3-fluorophenyl)methoxy]aniline
• 3-Chloro-4-[(3-fluorophenyl)methoxy]benzenamine
• 4-(3-Fluorobenzyloxy)-3-chloroaniline
• Benzenamine, 3-chloro-4-[(3-fluorophenyl)methoxy]-
• [3-Chloro-4-(3-fluorobenzyloxy)phenyl]amine

Benzenamine, 3-chloro-4-[(3-fluorophenyl)methoxy]-

CAS: 202197-26-0

• Formula: C₁₃H₁₁ClFNO
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 251.68394319999996

Lapatinib Impurity 18

CAS: 202197-26-0

• Formula: C₁₃H₁₁ClFNO
• Color and Shape: Pale Grey Solid
• Molecular weight: 251.69

Lapatinib Impurity 18-d4

CAS: 202197-26-0

• Formula: C₁₃H₇D₄ClFNO
• Color and Shape: White To Off-White Solid
• Molecular weight: 255.71

3-Chloro-4-(3-fluorobenzyloxy)aniline

CAS: 202197-26-0

• Formula: C₁₃H₁₁ClFNO
• Purity: >98.0%(GC)(T)
• Color and Shape: White to Gray to Red powder to crystal
• Molecular weight: 251.69

3-Chloro-4-[(3-fluorobenzyl)oxy]aniline

CAS: 202197-26-0

• Purity: 98+%
• Color and Shape: Grey Solid
• Molecular weight: 251.68g/mol

3-Chloro-4-(3-fluorobenzyloxy)aniline

CAS: 202197-26-0

Applications 3-Chloro-4-(3-fluorobenzyloxy)aniline is an intermediate in the synthesis of Lapatinib (L175800). References Petrov, K., et …

• Formula: C₁₃H₁₁ClFNO
• Color and Shape: Brown
• Molecular weight: 251.68

3-Chloro-4-[(3-fluorobenzyl)oxy]aniline

CAS: 202197-26-0

• Purity: 97.0%
• Color and Shape: Solid, Brown powder
• Molecular weight: 251.69000244140625

3-Chloro-4-(3-fluorobenzyloxy)aniline

CAS: 202197-26-0

3-Chloro-4-(3-fluorobenzyloxy)aniline is a potent inhibitor of the epidermal growth factor receptor (EGFR), which is a …

• Formula: C₁₃H₁₁ClFNO
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 251.68 g/mol