CAS 202409-33-4: Etoricoxib

Description:Etoricoxib is a selective cyclooxygenase-2 (COX-2) inhibitor, primarily used as a nonsteroidal anti-inflammatory drug (NSAID) for the treatment of pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and acute pain. Its chemical formula is C18H15N3O4S, and it features a sulfonamide group, which contributes to its pharmacological activity. Etoricoxib exhibits a high affinity for COX-2, leading to reduced production of prostaglandins, which are mediators of inflammation and pain. The substance is typically administered orally and has a relatively long half-life, allowing for once-daily dosing. Common side effects may include gastrointestinal issues, cardiovascular risks, and potential renal effects, similar to other NSAIDs. Etoricoxib is contraindicated in certain populations, such as those with a history of cardiovascular disease or severe renal impairment. Overall, its targeted action on COX-2 makes it a valuable option in pain management, though careful consideration of its safety profile is essential in clinical use.

Formula:C₁₈H₁₅ClN₂O₂S

InChI:InChI=1S/C18H15ClN2O2S/c1-12-3-4-14(10-20-12)18-17(9-15(19)11-21-18)13-5-7-16(8-6-13)24(2,22)23/h3-11H,1-2H3

InChI key:InChIKey=MNJVRJDLRVPLFE-UHFFFAOYSA-N

SMILES:O=S(=O)(C1=CC=C(C=C1)C2=CC(Cl)=CN=C2C=3C=NC(=CC3)C)C

Synonyms:
2,3′-Bipyridine, 5-chloro-6′-methyl-3-[4-(methylsulfonyl)phenyl]-
5-Chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine
5-Chloro-6'-Methyl-3-[4-(Methylsulfonyl)Phenyl]-2,3'-Bipyridine
Algix
Arcoxia
Etobrix
Etocox
Etosaid
Etoxib
Etropain
See more synonyms
Kingcox
Mk 0663
Mk 663
Nucoxia
Tauxib
Torcoxia
Etoricoxib

Found 15 products.

Product data	Purity	Price range	Estimated delivery
2,3'-Bipyridine, 5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]- REF: IN-DA002878CAS: 202409-33-4	98%	To inquire	Thu 27 Mar 25
Etoricoxib REF: TM-T1574CAS: 202409-33-4	99.68%	35.00 €~250.00 €	Thu 27 Mar 25
Etoricoxib-13C-d3 REF: 4Z-E-453CAS: 202409-33-4	- - -	To inquire	Fri 28 Mar 25
Etoricoxib REF: 4Z-E-451CAS: 202409-33-4	- - -	232.00 €~1,017.00 €	Fri 28 Mar 25
Etoricoxib REF: 7W-GP7329CAS: 202409-33-4	≥ 98.5% (dried basis)	53.00 €~148.00 €	Fri 28 Mar 25
Etoricoxib REF: 04-C13365000CAS: 202409-33-4	- - -	To inquire	Tue 01 Apr 25
Etoricoxib REF: 86-MM0965.00CAS: 202409-33-4	- - -	1,494.00 €	Tue 01 Apr 25
Etoricoxib REF: AC-46338CAS: 202409-33-4	- - -	132.00 €	Tue 01 Apr 25
Etoricoxib REF: 3B-E1492CAS: 202409-33-4	>95.0%(T)(HPLC)	49.00 €~146.00 €	Tue 01 Apr 25
Etoricoxib-d6 REF: TR-E934107CAS: 202409-33-4	- - -	405.00 €~2,745.00 €	Tue 08 Apr 25
Etoricoxib REF: TR-E934100CAS: 202409-33-4	- - -	355.00 €~1,579.00 €	Tue 08 Apr 25
Etoricoxib - Bio-X ™ REF: 3D-BC164436CAS: 202409-33-4	Min. 95%	145.00 €	Mon 07 Apr 25
5-Chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine REF: 3D-FC23204CAS: 202409-33-4	Min. 95%	159.00 €~1,464.00 €	Mon 07 Apr 25
Etoricoxib-d9 REF: TR-E934109CAS: 202409-33-4	- - -	2,320.00 €	Wed 07 May 25
Etoricoxib-13C,d3 REF: TR-E934104CAS: 202409-33-4	- - -	14,422.00 €	Wed 07 May 25