CAS 202656-13-1: tris(hydroxymethyl-D3)amino-D2-methane

Description: Tris(hydroxymethyl)aminomethane, commonly referred to as TRIS, is a chemical compound often used as a buffering agent in biochemical and molecular biology applications. The specific variant you mentioned, tris(hydroxymethyl-D3)amino-D2-methane, indicates isotopic labeling, where deuterium (D) is incorporated into the molecule, enhancing its utility in certain analytical techniques like NMR spectroscopy. TRIS is characterized by its ability to maintain a stable pH in biological systems, typically within the physiological range of pH 7 to 9. It is soluble in water and exhibits low toxicity, making it suitable for use in various laboratory settings. The compound has a relatively high molecular weight and is often used in buffer solutions for electrophoresis, cell culture, and enzyme assays. Its stability and compatibility with biological macromolecules make it a preferred choice in many experimental protocols. Additionally, TRIS can undergo protonation and deprotonation, which contributes to its buffering capacity.

Synonyms:

• Tris(hydroxymethyl-d3)amino-d2-methane solution

TRIS-d11 (crystalline)

CAS: 202656-13-1

• Formula: (DOCD₂)₃CND₂
• Purity: 98 atom % D
• Color and Shape: White Solid
• Molecular weight: 132.14294

TRIS-d11 (1M solution in D2O)

CAS: 202656-13-177-86-1 7789-20-0

• Color and Shape: Colorless Liquid

Tris(hydroxymethyl-d3)amino-d2-methane

CAS: 202656-13-1

Tris(hydroxymethyl-d3)amino-d2-methane is a hydrogen bond acceptor for the hydroxylase. It interacts with 2-hydroxyglutarate, which is …

• Formula: C₄H₁₁NO₃
• Purity: Min. 95%
• Molecular weight: 132.2 g/mol