CymitQuimica logo

CAS 202656-13-1

:

tris(hydroxymethyl-D3)amino-D2-methane

Description:
Tris(hydroxymethyl)aminomethane, commonly referred to as TRIS, is a chemical compound often used as a buffering agent in biochemical and molecular biology applications. The specific variant you mentioned, tris(hydroxymethyl-D3)amino-D2-methane, indicates isotopic labeling, where deuterium (D) is incorporated into the molecule, enhancing its utility in certain analytical techniques like NMR spectroscopy. TRIS is characterized by its ability to maintain a stable pH in biological systems, typically within the physiological range of pH 7 to 9. It is soluble in water and exhibits low toxicity, making it suitable for use in various laboratory settings. The compound has a relatively high molecular weight and is often used in buffer solutions for electrophoresis, cell culture, and enzyme assays. Its stability and compatibility with biological macromolecules make it a preferred choice in many experimental protocols. Additionally, TRIS can undergo protonation and deprotonation, which contributes to its buffering capacity.
Formula:C4H11NO3
InChI:InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2/i1D2,2D2,3D2,6D,7D,8D/hD2
InChI key:LENZDBCJOHFCAS-RNVFPDRBSA-N
SMILES:[2H]C([2H])(C(C([2H])([2H])O[2H])(C([2H])([2H])O[2H])N([2H])[2H])O[2H]
Synonyms:
  • Tris(hydroxymethyl-d3)amino-d2-methane solution
Found 2 products.