CAS 2030-63-9
:Clofazimine
Description:
Clofazimine is a synthetic compound primarily used as an antibiotic in the treatment of leprosy and certain types of mycobacterial infections. It belongs to the class of riminophenazine dyes and exhibits a distinctive red to brown color. Clofazimine is characterized by its lipophilic nature, which allows it to accumulate in tissues, particularly in macrophages, where it exerts its antimicrobial effects. The mechanism of action involves binding to mycobacterial DNA, disrupting the function of the bacteria and inhibiting their growth. Clofazimine has a long half-life, which contributes to its effectiveness in treating chronic infections. It is known for its side effects, including skin discoloration, gastrointestinal disturbances, and potential for hypersensitivity reactions. Due to its unique properties, clofazimine is often used in combination with other antitubercular agents to enhance therapeutic efficacy and reduce the risk of resistance development. Its use is generally well-regulated, and it is classified as a prescription medication in many countries.
Formula:C27H22Cl2N4
InChI:InChI=1S/C27H22Cl2N4/c1-17(2)30-24-16-27-25(15-23(24)31-20-11-7-18(28)8-12-20)32-22-5-3-4-6-26(22)33(27)21-13-9-19(29)10-14-21/h3-17,31H,1-2H3
InChI key:InChIKey=WDQPAMHFFCXSNU-UHFFFAOYSA-N
SMILES:N(C(C)C)=C1C=C2N(C=3C(N=C2C=C1NC4=CC=C(Cl)C=C4)=CC=CC3)C5=CC=C(Cl)C=C5
Synonyms:- (3E)-N,5-bis(4-chlorophenyl)-3-(propan-2-ylimino)-3,5-dihydrophenazin-2-amine
- 2-(4-Chloroanilino)-3-isopropylimino-5-(4-chlorophenyl)-3,5-dihydrophenazine
- 2-Phenazinamine, N,5-bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-
- 2-p-Chloroanilino-5-p-chlorophenyl-3,5-dihydro-3-isopropyliminophenazine
- 3-(p-Chloroanilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)phenazine
- 4-chloro-N-(5-(4-chlorophenyl)-3,5-dihydro-3-isopropyliminophenazin-2-yl)aniline
- B 663
- B 663 (pharmaceutical)
- Chlofazimine
- Clofacimira
- Clofazimin
- G 30320
- Hansepran
- Lampren
- Lamprene
- N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-2-phenazinamine
- Nsc 141046
- See more synonyms
Filter by
Purity percentage
0
100
|
0
|
50
|
90
|
95
|
100
- Lower prices
- Higher prices
- Lower purities
- Higher purities
- Faster estimated delivery
Clofazimine
CAS:Formula:C27H22Cl2N4Purity:>98.0%(HPLC)(T)Color and Shape:Yellow to Amber to Dark red powder to crystalMolecular weight:473.40Clofazimine
CAS:ClofazimineFormula:C27H22Cl2N4Purity:99.6%Color and Shape:White SolidMolecular weight:472.12215CLOFAZIMINE FOR SYSTEM SUITABILITY CRS
CAS:CLOFAZIMINE FOR SYSTEM SUITABILITY CRSFormula:C27H22Cl2N4Molecular weight:473.3964Clofazimine
CAS:Anti-infective agents, nesoiFormula:C27H22Cl2N4Color and Shape:Red Brown Fine Crystalline PowderMolecular weight:472.12215Clofazimine
CAS:Clofazimine, a phenazine dye, has anti-mycobacterial/inflammatory effects, targeting Mycobacterium leprae and others.Formula:C27H22Cl2N4Purity:98.23% - 99.85%Color and Shape:Red SolidMolecular weight:473.40Clofazimine
CAS:Formula:C27H22Cl2N4Purity:≥ 98.0%Color and Shape:Brown to red crystalline powderMolecular weight:473.40Clofazimine (Standard)
CAS:Clofazimine (Standard) is a reference standard for research and analysis in studies involving Clofazimine. Clofazimine (NSC-141046) is a phenazine dye with anti-mycobacterial and anti-inflammatory activities. Clofazimine has a slow bactericidal effect on Mycobacterium leprae and is active against various other Mycobacteria.Formula:C27H22Cl2N4Molecular weight:473.40Clofazimine-d7
CAS:Controlled ProductApplications Labelled Clofazimine (C324300). Antibacterial (tuberculostatic, leprostatic).
References Doak, A., et al.: J. Med. Chem., 53, 4259 (2010), Rodgers, A., et al.: Chem. Res. Toxicol., 23, 724 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),Formula:C27H15D7Cl2N4Color and Shape:NeatMolecular weight:480.44Clofazimine
CAS:N,5-Bis(4-chlorophenyl)-3-(isopropylimino)-3,5-dihydrophenazin-2-amineFormula:C27H22Cl2N4Purity:98%Molecular weight:473.4
