CAS 2034181-36-5

AMPA receptor modulator-2

CAS: 2034181-36-5

AMPA receptor modulator-2

Purity: ≥98%

Molecular weight: 404.29g/mol

Ref: 54-BUP07454

6-[2,5-Bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]-2(3H)-benzothiazolone

CAS: 2034181-36-5

6-[2,5-Bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]-2(3H)-benzothiazolone is a novel small molecule that has been shown to be a potent and selective activator of the protein kinase C (PKC) family. It binds to the PKC alpha isoform with an IC50 of 0.5 nM and displays low nanomolar activity against PKC beta and gamma isoforms. The activation of PKC alpha by 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]-2(3H)-benzothiazolone leads to increased phosphorylation of proteins involved in cell signaling pathways, including G protein coupled receptors (GPCRs), tyrosine kinases and

Formula: C₁₅H₆F₆N₄OS

Purity: Min. 95%

Molecular weight: 404.3 g/mol

Ref: 3D-JGD18136

AMPA receptor modulator-2

CAS: 2034181-36-5

AMPA receptor modulator-2 is a modulator of AMPA receptor. The pIC50 value for TARPγ2 dependent AMPA receptor is 10.1.

Formula: C₁₅H₆F₆N₄OS

Purity: 99.8%

Color and Shape: Solid

Molecular weight: 404.29

Ref: TM-T37734