
CAS 2034181-36-5
:Formula:C15H6F6N4OS
InChI:InChI=1S/C15H6F6N4OS/c16-14(17,18)10-4-3-8-11(24-10)25(12(22-8)15(19,20)21)6-1-2-7-9(5-6)27-13(26)23-7/h1-5H,(H,23,26)
InChI key:BPZAQDCXSKBMKM-UHFFFAOYSA-N
SMILES:C1=CC2=C(C=C1N3C4=C(C=CC(=N4)C(F)(F)F)N=C3C(F)(F)F)SC(=O)N2
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AMPA receptor modulator-2
CAS:AMPA receptor modulator-2Formula:C15H6F6N4OSPurity:99.5%Molecular weight:404.296-(2,5-Bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl)benzo[d]thiazol-2(3H)-one
CAS:Formula:C15H6F6N4OSPurity:95%Color and Shape:SolidMolecular weight:404.28986-[2,5-Bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]-2(3H)-benzothiazolone
CAS:6-[2,5-Bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]-2(3H)-benzothiazolone is a novel small molecule that has been shown to be a potent and selective activator of the protein kinase C (PKC) family. It binds to the PKC alpha isoform with an IC50 of 0.5 nM and displays low nanomolar activity against PKC beta and gamma isoforms. The activation of PKC alpha by 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]-2(3H)-benzothiazolone leads to increased phosphorylation of proteins involved in cell signaling pathways, including G protein coupled receptors (GPCRs), tyrosine kinases and
Formula:C15H6F6N4OSPurity:Min. 95%Molecular weight:404.3 g/molAMPA receptor modulator-2
CAS:AMPA receptor modulator-2 is a modulator of AMPA receptor. The pIC50 value for TARPγ2 dependent AMPA receptor is 10.1.Formula:C15H6F6N4OSPurity:99.8%Color and Shape:SolidMolecular weight:404.29Ref: TM-T37734
1mg116.00€5mg281.00€1mL*10mM (DMSO)310.00€10mg371.00€25mg595.00€50mg857.00€100mg1,188.00€




