CAS 20380-11-4
:(25R)-26-Hydroxycholesterol
Description:
(25R)-26-Hydroxycholesterol is a sterol compound that plays a significant role in cholesterol metabolism and homeostasis. It is a hydroxylated derivative of cholesterol, specifically featuring a hydroxyl group at the 26th carbon position and a specific stereochemistry at the 25th carbon. This compound is primarily involved in the regulation of cholesterol levels within cells and has been shown to influence various biological processes, including inflammation and immune responses. (25R)-26-Hydroxycholesterol can modulate the activity of liver X receptors (LXRs), which are nuclear receptors that regulate lipid metabolism and cholesterol efflux. Additionally, it has been implicated in the pathophysiology of certain diseases, including atherosclerosis and neurodegenerative disorders. The substance is typically studied in the context of its physiological effects and potential therapeutic applications, particularly in relation to cardiovascular health and metabolic disorders. Its CAS number, 20380-11-4, is a unique identifier used to facilitate the identification and study of this specific chemical compound in scientific literature and databases.
Formula:C27H46O2
InChI:InChI=1S/C27H46O2/c1-18(17-28)6-5-7-19(2)23-10-11-24-22-9-8-20-16-21(29)12-14-26(20,3)25(22)13-15-27(23,24)4/h8,18-19,21-25,28-29H,5-7,9-17H2,1-4H3/t18-,19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
InChI key:InChIKey=FYHRJWMENCALJY-YSQMORBQSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@H](CCC[C@H](CO)C)C)[H])[H]
Synonyms:- (25R)-26-Hydroxycholesterol
- (25R)-Cholest-5-ene-3β,26-diol
- (3β,25R)-Cholest-5-ene-3,26-diol
- Cholest-5-ene-3,26-diol, (3β,25R)-
- Cholest-5-ene-3beta,26-diol, (25R)-
- Cholest-5-ene-3β,26-diol, (25R)-
- cholest-5-ene-3,26-diol, (3beta,25R)-
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Found 9 products.
Cholest-5-ene-3,26-diol, (3β,25R)-
CAS:Formula:C27H46O2Purity:98%Color and Shape:SolidMolecular weight:402.652927-Hydroxycholesterol
CAS:Formula:C27H46O2Purity:95%~99%Color and Shape:PowderMolecular weight:402.663(25R)-26-Hydroxycholesterol
CAS:Controlled Product<p>Applications (25R)-26-Hydroxycholesterol is a desmosterol metabolite that is found in the brain. 26-Hydroxycholesterol has been used as a biomarker for carbon cycling in the northwestern Mediterranean Sea.<br>References Meljon, A., et. al.: J. Lipid Res., 53, 2469 (2012); Christodoulou, S., et. al.: Marine Chem., 113, 25 (2009)<br></p>Formula:C27H46O2Color and Shape:NeatMolecular weight:402.6525,25r-Cholesten-3beta,26-diol
CAS:Controlled Product<p>5,25-Cholesten-3β,26-diol (5,25-DHD) is a hormone that belongs to the group of angiotensin system inhibitors. It is a potent antagonist of the angiotensin II type 1 receptor (AT1R). 5,25-DHD has been shown to inhibit hepatic steatosis and improve mitochondrial function in mice with high blood pressure. This drug also has significant cytotoxicity against tumor cells and acts as an effector protein for toll-like receptor 4 (TLR4). 5,25-DHD can bind to iron ions and transport them across the plasma membrane by binding to the ATP binding cassette transporter A1 (ABCA1). 5,25-DHD has been shown to have significant effects on brain functions such as neuronal death and growth factor β1.</p>Formula:C27H46O2Purity:Min. 95%Color and Shape:PowderMolecular weight:402.65 g/mol27-Hydroxycholesterol
CAS:<p>27-Hydroxycholesterol (25(R)-27-hydroxy Cholesterol) is a selective modulator of estrogen receptor and an agonist of the liver X receptor.</p>Formula:C27H46O2Purity:99.45% - 99.82%Color and Shape:SolidMolecular weight:402.65
