CAS: 204005-46-9 - Semaxinib

Formula: C₁₅H₁₄N₂O

InChI: InChI=1S/C15H14N2O/c1-9-7-10(2)16-14(9)8-12-11-5-3-4-6-13(11)17-15(12)18/h3-8,16H,1-2H3,(H,17,18)

InChI key: InChIKey=WUWDLXZGHZSWQZ-UHFFFAOYSA-N

SMILES: O=C1NC=2C=CC=CC2C1=CC=3NC(=CC3C)C

Synonyms:

• (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1,3-dihydro-2H-indol-2-one
• (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one
• (Z)-3-(3,5-Dimethylpyrrol-2-ylmethylene)indolin-2-one
• 2H-Indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-
• 3-((2,4-Dimethylpyrrol-5-YL)METHYLIDENYL)-2-indolonone
• 3-(3,5-Dimethyl-1H-pyrrol-2-ylmethylene)-1,3-dihydroindol-2-one
• 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one
• 3-[(3,5-Dimethylpyrrol-2-yl)methylene]indolin-2-one
• Nsc-696819
• Semaxanib
• Semaxinib
• Semoxind
• Su-5416
• Sugen 5416
• Tsu-16
• VEGFR2 receptor tyrosine kinase III

2H-Indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-

CAS: 204005-46-9

• Formula: C₁₅H₁₄N₂O
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 238.2845

SU 5416

CAS: 204005-46-9

• Formula: C₁₅H₁₄N₂O
• Molecular weight: 238.28

SU 5416

CAS: 204005-46-9

• Formula: C₁₅H₁₄N₂O
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Yellow to Orange powder to crystal
• Molecular weight: 238.29

Semaxinib

CAS: 204005-46-9

Semaxinib (SU5416): potent VEGFR2 inhibitor, 20x more selective over PDGFRβ, not active on InsR/EGFR/FGFR, blocks …

• Formula: C₁₅H₁₄N₂O
• Purity: 99.84%
• Color and Shape: Yellow To Yellow Orange
• Molecular weight: 238.28

SU 5416

CAS: 204005-46-9

Inhibitor of Flk-1/KDR receptor tyrosine kinases, a vascular endothelial growth factor receptor (VEGF) receptor expressed …

• Formula: C₁₅H₁₄N₂O
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 238.28 g/mol

SU 5416

CAS: 204005-46-9

Applications SU 5416 is a vascular endothelial growth factor receptor blocker that may induce severe …

• Formula: C₁₅H₁₄N₂O
• Color and Shape: Neat
• Molecular weight: 238.28