Semaxinib
CAS: 204005-46-9
Ref. TM-T2064
| 5mg | 52.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 117.00 € | ||
| 50mg | 164.00 € | ||
| 100mg | 220.00 € | ||
| 1ml*10 (DMSO) | 54.00 € |
Estimated delivery in United States, on Wednesday 15 May 2024
Product Information
Name:
Semaxinib
Synonyms:
- SU5416
- (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1,3-dihydro-2H-indol-2-one
- (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one
- (Z)-3-(3,5-Dimethylpyrrol-2-ylmethylene)indolin-2-one
- 2H-Indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-
- 3-((2,4-Dimethylpyrrol-5-YL)METHYLIDENYL)-2-indolonone
- 3-(3,5-Dimethyl-1H-pyrrol-2-ylmethylene)-1,3-dihydroindol-2-one
- 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one
- 3-[(3,5-Dimethylpyrrol-2-yl)methylene]indolin-2-one
- Nsc-696819
- See more synonyms
- Semaxanib
- Semoxind
- Su-5416
- Sugen 5416
- Tsu-16
- VEGFR2 receptor tyrosine kinase III
CAS:
Description:
Semaxinib (SU5416) is a potent and selective VEGFR2 inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR than PDGFRβ, lack of activity against InsR, EGFR, and FGFR. Semaxanib reversibly inhibits ATP binding to the tyrosine kinase domain of vascular endothelial growth factor receptor 2 (VEGFR2), which may inhibit VEGF-stimulated endothelial cell migration and proliferation and reduce the tumor microvasculature.
Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
238.28
Formula:
C15H14N2O
Purity:
99.15%
Color/Form:
Yellow To Yellow Orange
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
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