CAS 204394-70-7

Pyrimidine, 4-chloro-2-(4-pyridinyl)-6-(trifluoromethyl)-

Description:

Pyrimidine, 4-chloro-2-(4-pyridinyl)-6-(trifluoromethyl)-, identified by CAS number 204394-70-7, is a heterocyclic organic compound featuring a pyrimidine ring substituted with a chlorine atom and a trifluoromethyl group. The presence of the 4-pyridinyl substituent indicates that there is an additional pyridine ring attached to the pyrimidine structure, enhancing its aromatic character. This compound is characterized by its relatively high stability due to the resonance within the aromatic systems and the electron-withdrawing nature of the trifluoromethyl group, which can influence its reactivity and solubility. It is typically used in medicinal chemistry and research due to its potential biological activity, particularly in the development of pharmaceuticals. The chlorine and trifluoromethyl groups can also impart unique electronic properties, making it a valuable compound for various synthetic applications. As with many halogenated compounds, appropriate safety measures should be taken when handling this substance, as it may pose health risks or environmental concerns.

Formula: C₁₀H₅ClF₃N₃

Synonyms:

• 4-chloro-2-(4-pyridyl)-6-(trifluoroMethyl)pyriMidine
• Pyrimidine, 4-chloro-2-(4-pyridinyl)-6-(trifluoromethyl)-
• 4-Chloro-2-(pyridin-4-yl)-6-(trifluoromethyl)pyrimidine

4-Chloro-2-(pyridin-4-yl)-6-(trifluoromethyl)pyrimidine

CAS: 204394-70-7

4-Chloro-2-(pyridin-4-yl)-6-(trifluoromethyl)pyrimidine

Formula: C₁₀H₅ClF₃N₃

Purity: 95%

Molecular weight: 259.615

Ref: 54-PC28165

4-Chloro-2-(4-pyridinyl)-6-(trifluoromethyl)-pyrimidine

CAS: 204394-70-7

4-Chloro-2-(4-pyridinyl)-6-(trifluoromethyl)pyrimidine is a potent anticancer compound that inhibits the polymerization of tubulin, leading to cell death. It has been shown to be effective in inducing apoptosis in cancer cells. The EC50 values for 4-chloro-2-(4-pyridinyl)-6-(trifluoromethyl)pyrimidine are 0.1 and 0.3 μM for t47d cells and A549 cells, respectively. This compound is also an inducer of apoptosis in cancer cells with an EC50 value of 1.0 μM for the A549 cell line.

Formula: C₁₀H₅ClF₃N₃

Purity: Min. 95%

Molecular weight: 259.62 g/mol

Ref: 3D-EIA39470