CAS 205393-22-2: Bortezomib-pinanediol

Description: Bortezomib-pinanediol, identified by its CAS number 205393-22-2, is a synthetic compound primarily known for its role as a proteasome inhibitor. It is a derivative of bortezomib, which is used in the treatment of multiple myeloma and certain types of lymphoma. The compound exhibits a complex structure that includes a boronic acid moiety, which is crucial for its mechanism of action, as it binds to the active site of the proteasome, disrupting protein degradation pathways. This inhibition leads to the accumulation of pro-apoptotic factors and cell cycle regulators, ultimately inducing apoptosis in cancer cells. Bortezomib-pinanediol may also possess unique pharmacokinetic properties due to the pinanediol component, potentially influencing its solubility and bioavailability. As with many pharmaceutical compounds, its efficacy and safety profile are subject to extensive research and clinical evaluation. Overall, bortezomib-pinanediol represents a significant advancement in targeted cancer therapies, contributing to the ongoing development of proteasome inhibitors in oncology.

Formula: C₂₉H₃₉BN₄O₄

Synonyms:

• Bortezomib pinanediol ester
• N-[(1S)-2-[[(1R)-1-[(3As,4S,6S,7Ar)-Hexahydro-3A,5,5-Trimethyl-4,6-Methano-1,3,2-Benzodioxaborol-2-Yl]-3-Methylbutyl]Amino]-2-Oxo-1-(Phenylmethyl)Ethyl]-2-Pyrazinecarboxamide
• N-[(1S)-1-Benzyl-2-({(1R)-3-Methyl-1-[(1S,2S,6R,8S)-2,9,9-Trimethyl-3,5-Dioxa-4-Boratricyclo[6.1.1.0~2,6~]Dec-4-Yl]Butyl}Amino)-2-Oxoethyl]-2-Pyrazinecarboxamide
• Bortezomib Intermediates Iii
• Bortezomib Intermediate III

BORTEZOMIB-PINANEDIOL

CAS: 205393-22-2

• Formula: C₂₉H₃₉BN₄O₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 518.4554

Bortezomib-pinanediol

CAS: 205393-22-2

Bortezomib-pinanediol is a proteasome inhibitor. is a prodrug of Bortezomib.

• Formula: C₂₉H₃₉BN₄O₄
• Purity: 97.5%
• Color and Shape: Yellow Solid
• Molecular weight: 518.46

Bortezomib Impurity 14

CAS: 205393-22-2

• Formula: C₂₉H₃₉BN₄O₄
• Molecular weight: 518.46

(1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methyl-butane-1-boronate

CAS: 205393-22-2

Please enquire for more information about (1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methyl-butane-1-boronate including the price, delivery time and more detailed …

• Formula: C₂₉H₃₉BN₄O₄
• Purity: Min. 95%
• Color and Shape: Solid
• Molecular weight: 518.46 g/mol

(1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methyl-butane-1-boronate (>90%)

CAS: 205393-22-2

Impurity Bortezomib Pinanediol Impurity Applications Intermediate in the preparation of Bortezomib (B675700), a dipeptidyl boronate …

• Formula: C₂₉H₃₉BN₄O₄
• Purity: >90%
• Color and Shape: Light Yellow
• Molecular weight: 518.46