CAS 2055397-28-7

3-Fluoro-5-(2-pyridinyl)benzoic acid 2-[(2-fluorophenyl)sulfonyl]hydrazide

Description:

3-Fluoro-5-(2-pyridinyl)benzoic acid 2-[(2-fluorophenyl)sulfonyl]hydrazide is a chemical compound characterized by its complex structure, which includes a benzoic acid moiety substituted with a fluorine atom and a pyridine ring. The presence of a hydrazide functional group indicates potential reactivity, particularly in forming hydrazones or participating in condensation reactions. The sulfonyl group attached to the hydrazide enhances the compound's polarity and solubility in polar solvents, which can influence its biological activity and interaction with other molecules. This compound may exhibit interesting pharmacological properties due to its structural features, making it a candidate for research in medicinal chemistry. Additionally, the presence of fluorine atoms often contributes to increased metabolic stability and lipophilicity, which can affect the compound's bioavailability. Overall, the unique combination of functional groups in this compound suggests potential applications in drug development and other chemical research areas.

Formula: C₁₈H₁₃F₂N₃O₃S

InChI: InChI=1S/C18H13F2N3O3S/c19-14-10-12(16-6-3-4-8-21-16)9-13(11-14)18(24)22-23-27(25,26)17-7-2-1-5-15(17)20/h1-11,23H,(H,22,24)

InChI key: InChIKey=QLXULUNLCRKWRD-UHFFFAOYSA-N

SMILES: C(NNS(=O)(=O)C1=C(F)C=CC=C1)(=O)C=2C=C(C=C(F)C2)C3=CC=CC=N3

Synonyms:

• 3-Fluoro-5-(2-pyridinyl)benzoic acid 2-[(2-fluorophenyl)sulfonyl]hydrazide
• Benzoic acid, 3-fluoro-5-(2-pyridinyl)-, 2-[(2-fluorophenyl)sulfonyl]hydrazide
• WM 1119

3-fluoro-N'-(2-fluorobenzenesulfonyl)-5-(pyridin-2-yl)benzohydrazide

CAS: 2055397-28-7

Formula: C₁₈H₁₃F₂N₃O₃S

Purity: %

Color and Shape: Solid

Molecular weight: 389.3759

Ref: IN-DA01DZ98

WM-1119

CAS: 2055397-28-7

WM-1119

Purity: ≥95%

Molecular weight: 389.38g/mol

Ref: 54-BUP13269

WM-1119

CAS: 2055397-28-7

WM-1119 is a highly potent, selective KAT6A/B inhibitor

Formula: C₁₈H₁₃F₂N₃O₃S

Purity: 96.59% - 99.58%

Color and Shape: Solid

Molecular weight: 389.38

Ref: TM-T4679

2-Fluoro-N'-(3-fluoro-5-(pyridin-2-yl)benzoyl)benzenesulfonohydrazide

CAS: 2055397-28-7

Purity: 95.0%

Molecular weight: 389.3800048828125

Ref: 10-F544415

WM 1119

CAS: 2055397-28-7

Selective and potent inhibitor of lysine acetyltransferases KAT6A and KAT6B with IC50 values in low nanomolar range. The compound is a reversible competitor of acetyl coenzyme A domain of KAT6A/B enzymes. It inhibits MYST-catalysed histone acetylation and was shown to arrest lymphoma progression in mice models. The compound opened the door to a new class of cancer therapeutics that could potentially direct the cancer cells in senescence or permanent dormancy.

Formula: C₁₈H₁₃F₂N₃O₃S

Purity: Min. 95%

Color and Shape: White/Off-White Solid

Molecular weight: 389.38 g/mol

Ref: 3D-BW166843