CAS 20554-84-1
:(-)-Parthenolide
Description:
(-)-Parthenolide is a sesquiterpene lactone primarily derived from the plant Tanacetum parthenium, commonly known as feverfew. This compound is characterized by its unique bicyclic structure, which includes a lactone functional group. (-)-Parthenolide exhibits a range of biological activities, including anti-inflammatory, anti-cancer, and anti-microbial properties, making it a subject of interest in pharmacological research. It is known to inhibit the nuclear factor kappa B (NF-κB) signaling pathway, which plays a crucial role in inflammation and cancer progression. The compound is typically found in a colorless to pale yellow liquid form and has a characteristic odor. Its solubility varies, being more soluble in organic solvents than in water. Due to its potential therapeutic effects, (-)-Parthenolide is being studied for its role in treating various conditions, including migraines and certain types of cancer. However, further research is needed to fully understand its mechanisms of action and potential applications in medicine.
Formula:C15H20O3
InChI:InChI=1/C15H20O3/c1-9-5-4-8-15(3)13(18-15)12-11(7-6-9)10(2)14(16)17-12/h5,11-13H,2,4,6-8H2,1,3H3/b9-5+/t11?,12-,13-,15+/m0/s1
InChI key:InChIKey=KTEXNACQROZXEV-PVLRGYAZSA-N
SMILES:C[C@]12[C@@]([C@@]3([C@](C(=C)C(=O)O3)(CC\C(\C)=C\CC1)[H])[H])(O2)[H]
Synonyms:- (1aR,4E,10aS,10bS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
- (1aR,4E,7aS,10aS,10bR)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
- (1aR,4E,7aS,10aS,10bR)-2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
- (1aR,4Z,7aS,10aS,10bS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
- (1aR,7aS,10aS,10bR)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
- (4E,7aS,10aS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
- (4Z)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
- 2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno(9,10)cyclodeca(1,2-b)furan-9(1aH)-one
- Germacra-1(10),11(13)-dien-12-oic acid, 4,5α-epoxy-6β-hydroxy-, γ-lactone
- Oxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one, 2,3,6,7,7a,8,10a,10b-octahydro-1a,5-dimethyl-8-methylene-, (1aR,4E,7aS,10aS,10bR)-
- Parthenolide
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Parthenolide
CAS:Formula:C15H20O3Purity:>97.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:248.32Parthenolide
CAS:Lactones, nesoiFormula:C15H20O3Color and Shape:White Crystalline PowderMolecular weight:248.14124Parthenolide
CAS:Formula:C15H20O3Purity:≥ 98.0%Color and Shape:White, off-white or pale yellow-brown powderMolecular weight:248.32Parthenolide
CAS:ParthenolideFormula:C15H20O3Purity:By hplc: 99.88% (Typical Value in Batch COA)Color and Shape:SolidMolecular weight:248.3175Parthenolide
CAS:Parthenolide analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.Formula:C15H20O3Purity:(HPLC) ≥95%Color and Shape:PowderMolecular weight:248.33(1aR,4E,7aS,10aS,10bR)-2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
CAS:Formula:C15H20O3Purity:97%Color and Shape:SolidMolecular weight:248.3175Parthenolide (Standard)
CAS:Parthenolide (Standard) is a reference standard for research and analysis in studies involving Parthenolide. Parthenolide ((-)-Parthenolide) is a natural sesquiterpene lactone that is an NF-κB inhibitor and also specifically inhibits HDAC1 protein, but is inactive against other class I/II HDACs. Parthenolide has anti-inflammatory, anti-tumor, and anti-viral activities.Formula:C15H20O3Molecular weight:248.32(3aS,9aR,10aR,10bS,E)-6,9a-Dimethyl-3-methylene-3a,4,5,8,9,9a,10a,10b-octahydrooxireno[2',3':9,10]cyclodeca[1,2-b]furan-2(3H)-one
CAS:(3aS,9aR,10aR,10bS,E)-6,9a-Dimethyl-3-methylene-3a,4,5,8,9,9a,10a,10b-octahydrooxireno[2',3':9,10]cyclodeca[1,2-b]furan-2(3H)-oneFormula:C15H20O3Purity:97% HPLCMolecular weight:248.32Parthenolide
CAS:Parthenolide ((-)-Parthenolide) is a natural sesquiterpene lactone that is an NF-κB and HDAC1 inhibitor with anti-inflammatory effect. Cost-effective and quality-assured.Formula:C15H20O3Purity:98.19% - 99.46%Color and Shape:SolidMolecular weight:248.32Parthenolide
CAS:LactoneFormula:C15H20O3Purity:≥ 90.0 % (HPLC)Color and Shape:PowderMolecular weight:248.32Parthenolide
CAS:Parthenolide is a sesquiterpene lactone, which is a bioactive compound derived from the plant species Tanacetum parthenium, commonly known as feverfew. This compound is primarily isolated from the aerial parts of the plant, where it is found in highest concentrations within the flowers and leaves. Parthenolide exerts its effects through several biochemical pathways, including the inhibition of nuclear factor-kappa B (NF-κB) signaling, which plays a critical role in inflammatory and immune responses. Additionally, it disrupts the activity of certain kinases and modulates the expression of genes involved in cell cycle regulation and apoptosis.Formula:C15H20O3Purity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:248.32 g/molParthenolide
CAS:M02322 - Parthenolide
Formula:C15H20O3Purity:97%Color and Shape:SolidMolecular weight:248.322
![(1aR,4E,7aS,10aS,10bR)-2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclod…](https://static.cymitquimica.com/products/IN/thumb/DA002A6V.jpg)
