CAS 205640-90-0

L-Leucinamide,5-oxo-L-prolyl-L-prolyl-L-leucyl-L-prolyl-L-a-aspartyl-L-cysteinyl-L-cysteinyl-L-arginyl-L-glutaminyl-L-lysyl-L-threonyl-L-cysteinyl-L-seryl-L-cysteinyl-L-arginyl-L-leucyl-L-tyrosyl-L-a-glutamyl-L-leucyl-L-leucyl-L-histidylglycyl-L-alanylgly

Description:

L-Leucinamide, 5-oxo-L-prolyl-L-prolyl-L-leucyl-L-prolyl-L-a-aspartyl-L-cysteinyl-L-cysteinyl-L-arginyl-L-glutaminyl-L-lysyl-L-threonyl-L-cysteinyl-L-seryl-L-cysteinyl-L-arginyl-L-leucyl-L-tyrosyl-L-a-glutamyl-L-leucyl-L-leucyl-L-histidylglycyl-L-alanylgly, with CAS number 205640-90-0, is a complex peptide-like compound characterized by a long chain of amino acids. This substance features multiple L-amino acids, including leucine, proline, aspartic acid, cysteine, arginine, glutamine, lysine, threonine, serine, tyrosine, histidine, and alanine, which contribute to its structural and functional properties. The presence of various amino acids suggests potential biological activity, possibly influencing protein synthesis or acting as a signaling molecule. The compound's structure may exhibit unique conformational characteristics due to the arrangement of its amino acid residues, which can affect its solubility, stability, and interaction with biological systems. Additionally, the presence of functional groups associated with the amino acids may allow for various chemical reactions, making it of interest in biochemical research and potential therapeutic applications.

Formula: C₁₅₂H₂₄₃N₄₇O₄₄S₄

Synonyms:

• OrexinA (human)
• Bovine orexin A
• Human orexin A
• Mouse orexin A
• Orexin A (swine)
• Pig orexin A
• Rat orexin A
• Pyr-Pro-Leu-Pro-Asp-Cys-Cys-Arg-Gln-Lys-Thr-Cys-Ser-Cys-Arg-Leu-Tyr-Glu-Leu-Leu-His-Gly-Ala-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Leu-Nh2

Orexin A (human, mouse, rat)

CAS: 205640-90-0

Orexin A (OXA, hypocretin-1) is a hypothalamic neuropeptide regulating the feeding behavior. Central administration of orexin A to rats stimulated food consumption in a dose-dependent manner. The effect persisted at 4 h after injection, as orexin A seems to be resistant to peptidases. Orexin A specifically binds a G protein-coupled receptor, OX₁R (IC₅₀ = 20 nM to displace 50 % of radiolabeled orexin A bound to this receptor). Orexin A produced in the amygdala induces wakefulness and plays a role in the induction of human emotions. Narcolepsy has been associated with orexin deficiency. The peptide also corresponds to bovine, canine, ovine, and porcine orexin A.

Formula: C₁₅₂H₂₄₃N₄₇O₄₄S₄

Purity: 95.9%

Color and Shape: White Lyophilisate

Molecular weight: 3561.16

Ref: 01-4028262

PYR-PRO-LEU-PRO-ASP-CYS-CYS-ARG-GLN-LYS-THR-CYS-SER-CYS-ARG-LEU-TYR-GLU-LEU-LEU-HIS-GLY-ALA-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-LEU-NH2

CAS: 205640-90-0

Formula: C₁₅₂H₂₄₃N₄₇O₄₄S₄

Purity: 97%

Molecular weight: 3561.1043

Ref: IN-DA00BCJT

Orexin A (human, rat, mouse)

CAS: 205640-90-0

Orexin A, a 33 AA neuropeptide in humans, rats, mice, influences various processes, studied in pancreatic function and as an OX1R antagonist.

Formula: C₁₅₂H₂₄₃N₄₇O₄₄S₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 3561.1

Ref: TM-TP1301

Orexin A

CAS: 205640-90-0

Orexin A

Purity: (hplc): 94.7% (tfa) (Typical Value in Batch COA)

Color and Shape: white lyophilisate

Molecular weight: 3,565.14g/mol

Ref: 54-BIBA1007

Orexin A (human) TFA

CAS: 205640-90-0

Orexin A (human) TFA is a high quality reagent that can be used as an intermediate in the synthesis of complex compounds, useful for research and development. It has many potential uses, including as a fine chemical, speciality chemical and reaction component. Orexin A (human) TFA is a versatile building block with many applications, such as being a useful scaffold or building block in reactions where it can be used in the synthesis of other compounds. It is also a valuable research chemical that can be used to study orexin receptors and their ligands.

Formula: C₁₅₂H₂₄₃N₄₇O₄₄S₄•C₂HF₃O₂

Purity: Min. 95 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 3,675.13 g/mol

Ref: 3D-FO109201

Orexin-A (Human)

CAS: 205640-90-0

This Orexin A (Human) product has disulfide bonds between Cys6-Cys12 and Cys7-Cys14, is sourced from: rat, mouse, bovine and is available as a 0.1mg vial. Orexin A is an isoform of orexin and is a neuropeptide produced in the cells of the hypothalamus. Orexins are involved in sleep cycles through exciting neurons and affecting acetylcholine, histamine, dopamine and norepinephrine systems.

Formula: C₁₅₂H₂₄₃N₄₇O₄₄S₄

Purity: Min. 95%

Molecular weight: 3,561.1 g/mol

Ref: 3D-POR-4346-S