CAS 2083627-02-3

Formula: C17H15N5O3S

InChI: InChI=1S/C17H15N5O3S/c1-26(23,24)14-6-4-12(5-7-14)15-10-19-17(22-11-20-21-16(15)22)18-9-13-3-2-8-25-13/h2-8,10-11H,9H2,1H3,(H,18,19)

InChI key: DYIRSNMPIZZNBK-UHFFFAOYSA-N

SMILES: CS(=O)(=O)C1=CC=C(C=C1)C2=CN=C(N3C2=NN=C3)NCC4=CC=CO4

EED226

CAS: 2083627-02-3

EED226

Formula: C₁₇H₁₅N₅O₃S

Purity: ≥98%

Molecular weight: 369.4

Ref: 54-BUP10084

EED226

CAS: 2083627-02-3

EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.

Formula: C₁₇H₁₅N₅O₃S

Purity: 98.14% - 99.33%

Color and Shape: Solid

Molecular weight: 369.4

Ref: TM-T3458

EED226

CAS: 2083627-02-3

N-(Furan-2-ylmethyl)-8-(4-(methylsulfonyl)phenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine

Formula: C₁₇H₁₅N₅O₃S

Purity: 98%

Molecular weight: 369.4

Ref: IN-DG763776

EED 226 monohydrate

CAS: 2083627-02-3

Potent and selective inhibitor of polycomb repressive complex 2 (PRC2), by binding to the K27me3-pocket of the regulatory EED subunit. Inhibits H3K27 methylation in histone 3. Has anti-tumor activity in murine xenograft models. Synergistic with EZH2 inhibitor against cancer cell growth.

Formula: C₁₇H₁₅N₅O₃S·H₂O

Purity: Min. 95%

Color and Shape: White To Yellow Solid

Molecular weight: 387.41 g/mol

Ref: 3D-BE165158

EED226

CAS: 2083627-02-3

Purity: 98%

Molecular weight: 369.09

Ref: 10-F866775

N-(furan-2-ylmethyl)-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine

CAS: 2083627-02-3

Formula: C₁₇H₁₅N₅O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 369.3977

Ref: IN-DA01DDLM