CAS 2088834-68-6

Formula: C148H248N52O30S

InChI: InChI=1S/C148H248N52O30S/c1-10-82(7)117(199-131(218)102(55-57-113(156)202)184-120(207)95(47-29-64-170-143(158)159)178-119(206)89(154)76-115(204)205)139(226)189-94(44-21-26-61-151)130(217)198-118(83(8)11-2)140(227)196-109(75-86-79-177-91-41-18-16-39-88(86)91)135(222)193-107(73-84-36-13-12-14-37-84)133(220)185-101(54-56-112(155)201)127(214)195-110(77-114(157)203)136(223)183-97(49-31-66-172-145(162)163)121(208)180-96(48-30-65-171-144(160)161)122(209)186-103(58-71-231-9)128(215)179-93(43-20-25-60-150)125(212)194-108(74-85-78-176-90-40-17-15-38-87(85)90)134(221)182-92(42-19-24-59-149)124(211)190-104(45-22-27-62-152)141(228)200-70-35-53-111(200)137(224)187-98(50-32-67-173-146(164)165)123(210)181-100(52-34-69-175-148(168)169)129(216)197-116(81(5)6)138(225)188-99(51-33-68-174-147(166)167)126(213)192-106(72-80(3)4)132(219)191-105(142(229)230)46-23-28-63-153/h12-18,36-41,78-83,89,92-111,116-118,176-177H,10-11,19-35,42-77,149-154H2,1-9H3,(H2,155,201)(H2,156,202)(H2,157,203)(H,178,206)(H,179,215)(H,180,208)(H,181,210)(H,182,221)(H,183,223)(H,184,207)(H,185,220)(H,186,209)(H,187,224)(H,188,225)(H,189,226)(H,190,211)(H,191,219)(H,192,213)(H,193,222)(H,194,212)(H,195,214)(H,196,227)(H,197,216)(H,198,217)(H,199,218)(H,204,205)(H,229,230)(H4,158,159,170)(H4,160,161,171)(H4,162,163,172)(H4,164,165,173)(H4,166,167,174)(H4,168,169,175)/t82-,83-,89-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,116-,117-,118-/m0/s1

InChI key: DZSCQHSXWCONOW-MQUFQTSSSA-N

SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC4=CNC5=CC=CC=C54)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N6CCC[C@H]6C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(=O)O)N

PTD-N5-1

CAS: 2088834-68-6

PTD-N5-1 (N5-1) is an IRF5 inhibitory peptide. It can block the production of IL-12 induced by β-glucan in both wild-type and Clec2d-deficient bone marrow-derived dendritic cells (BMDC) that are activated by IFN-γ. PTD-N5-1 modulates antifungal immunity by inhibiting IRF5-mediated IL-12 production.

Formula: C₁₄₈H₂₄₈N₅₂O₃₀S

Color and Shape: Solid

Molecular weight: 3267.95

Ref: TM-TP3674