
CAS 2089293-61-6
:Formula:C23H29Cl2N3O
InChI:InChI=1S/C23H29Cl2N3O/c1-2-3-13-27-14-11-20(12-15-27)28(17-18-7-5-4-6-8-18)23(29)26-19-9-10-21(24)22(25)16-19/h4-10,16,20H,2-3,11-15,17H2,1H3,(H,26,29)
InChI key:VPHJABWIKCBGMC-UHFFFAOYSA-N
SMILES:CCCCN1CCC(CC1)N(CC2=CC=CC=C2)C(=O)NC3=CC(=C(C=C3)Cl)Cl
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1-Benzyl-1-(1-butylpiperidin-4-yl)-3-(3,4-dichlorophenyl)urea
CAS:Formula:C23H29Cl2N3OPurity:99%Molecular weight:434.4019NAcM-OPT
CAS:Inhibits N-Acetyl-mediated interaction between BE2M (E2 conjugating enzyme) and DCN1 (a component of E3 ligase complex). Also has inhibitory action on DCN2 and NEDD8 ubiquitin-like protein. Reduces anchorage-independent growth in DCN1-amplified cell line.Formula:C23H29Cl2N3OPurity:Min. 95%Color and Shape:solid.Molecular weight:434.4 g/molNAcM-OPT
CAS:NAcM-OPT is a specific, reversible inhibitor targeting N-Acetyl-UBE2M interaction with DCN1 (IC50: 79 nM).Formula:C23H29Cl2N3OPurity:99.93%Color and Shape:SolidMolecular weight:434.402




