CAS 2091134-68-6

AZD-4205

Description:

AZD-4205 is a chemical compound that has garnered attention in pharmaceutical research, particularly for its potential therapeutic applications. It is classified as a selective antagonist of the orexin receptor, which plays a crucial role in regulating sleep-wake cycles and appetite. The compound's mechanism of action involves blocking the orexin receptors, thereby influencing neurobiological pathways associated with sleep disorders and possibly obesity. AZD-4205 is characterized by its specific binding affinity to the orexin receptors, which distinguishes it from other compounds in the same class. Its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, are essential for determining its efficacy and safety profile in clinical settings. Ongoing studies aim to evaluate its therapeutic potential, side effects, and overall impact on conditions like insomnia and other sleep-related disorders. As research progresses, AZD-4205 may contribute to the development of new treatments that target orexin signaling pathways.

Golidocitinib

CAS: 2091134-68-6

Golidocitinib (AZD4205) is a selective JAK1 inhibitor (IC50: 73 nM) and weakly inhibits JAK2/JAK3 (IC50: >14.7, >30 μM).

Formula: C₂₅H₃₁N₉O₂

Purity: 98.87% - 99.88%

Color and Shape: Yellow Solid

Molecular weight: 489.57

Ref: TM-T10431

(R)-N-(3-{2-[(3-Methoxy-1-methyl-1H-pyrazol-4-yl)amino]pyrimidin-4-yl}-1H-indol-7-yl)-2-(4-methylpiperazin-1-yl)propanamide

CAS: 2091134-68-6

Formula: C₂₅H₃₁N₉O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 489.5727

Ref: IN-DA01FNPZ

Golidocitinib

CAS: 2091134-68-6

Golidocitinib

Formula: C₂₅H₃₁N₉O₂

Purity: ≥98%

Molecular weight: 489.57

Ref: 54-BUP12967

Golidocitinib

CAS: 2091134-68-6

Formula: C₂₅H₃₁N₉O₂

Molecular weight: 489.58

Ref: 4Z-G-228001

Golidocitinib

CAS: 2091134-68-6

(R)-N-(3-(2-((3-Methoxy-1-methyl-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)-1H-indol-7-yl)-2-(4-methylpiperazin-1-yl)propanamide

Formula: C₂₅H₃₁N₉O₂

Purity: 98%

Molecular weight: 489.57

Ref: IN-DG00791712

AZD4205

CAS: 2091134-68-6

AZD4205 is an investigational therapeutic agent, which is a small molecule inhibitor developed by AstraZeneca. It is designed to target specific signaling pathways involved in cancer cell proliferation and survival. The source of AZD4205 lies in the meticulous synthesis of a compound specifically engineered to interfere with aberrant molecular processes within cancer cells.

Formula: C₂₅H₃₁N₉O₂

Purity: Min. 95%

Molecular weight: 489.57 g/mol

Ref: 3D-BA177711