CAS 209410-46-8: 5-(2,6-Dichlorophenyl)-2-[(2,4-difluorophenyl)thio]-6H-pyrimido[1,6-b]pyridazin-6-one

Description: 5-(2,6-Dichlorophenyl)-2-[(2,4-difluorophenyl)thio]-6H-pyrimido[1,6-b]pyridazin-6-one, with the CAS number 209410-46-8, is a synthetic organic compound characterized by its complex heterocyclic structure. This compound features a pyrimidine and pyridazine core, which contributes to its potential biological activity. The presence of dichlorophenyl and difluorophenyl groups indicates significant halogenation, which can enhance lipophilicity and influence the compound's interaction with biological targets. The thioether linkage introduces sulfur into the structure, potentially affecting its reactivity and solubility. This compound may exhibit pharmacological properties, making it of interest in medicinal chemistry, particularly in the development of new therapeutic agents. Its specific characteristics, such as melting point, solubility, and spectral data, would typically be determined through experimental methods. Overall, the unique structural features of this compound suggest it could play a role in various chemical and biological applications.

Formula: C₁₉H₉Cl₂F₂N₃OS

InChI: InChI=1S/C19H9Cl2F2N3OS/c20-11-2-1-3-12(21)17(11)18-14-5-7-16(25-26(14)9-24-19(18)27)28-15-6-4-10(22)8-13(15)23/h1-9H

InChI key: InChIKey=VEPKQEUBKLEPRA-UHFFFAOYSA-N

SMILES: O=C1N=CN2N=C(SC3=CC=C(F)C=C3F)C=CC2=C1C=4C(Cl)=CC=CC4Cl

Synonyms:

• 5-(2,6-Dichlorophenyl)-2-(2,4-difluorophenyl)sulfanylpyridazino[6,1-f]pyrimidin-6-one
• 5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)sulfanyl]-6H-pyrimido[1,6-b]pyridazin-6-one
• 6H-Pyrimido[1,6-b]pyridazin-6-one, 5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)thio]-
• Neflamapimod
• Vd 31745
• Vrt 031745
• Vx-745
• 5-(2,6-Dichlorophenyl)-2-[(2,4-difluorophenyl)thio]-6H-pyrimido[1,6-b]pyridazin-6-one

6H-Pyrimido[1,6-b]pyridazin-6-one, 5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)thio]-

CAS: 209410-46-8

• Formula: C₁₉H₉Cl₂F₂N₃OS
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 436.2621

Neflamapimod

CAS: 209410-46-8

• Purity: ≥98%
• Molecular weight: 436.26g/mol

VX-745

CAS: 209410-46-8

• Formula: C₁₉H₉Cl₂F₂N₃OS
• Purity: 99.8% (Typical Value in Batch COA)
• Color and Shape: yellow solid
• Molecular weight: 436.26g/mol

VX-745

CAS: 209410-46-8

Neflamapimod

CAS: 209410-46-8

Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity …

• Formula: C₁₉H₉Cl₂F₂N₃OS
• Purity: 99.02% - ≥95%
• Color and Shape: Solid
• Molecular weight: 436.26

5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)thio)-6H-pyrimido[1,6-b]pyridazin-6-one

CAS: 209410-46-8

• Purity: 95.0%
• Molecular weight: 436.260009765625

VX 745

CAS: 209410-46-8

Applications VX 745 is a potent and selective inhibitor of p38α mitogen-activated protein (MAP) kinase. …

• Formula: C₁₉H₉Cl₂F₂N₃OS
• Color and Shape: Neat
• Molecular weight: 436.26

Neflamapimod

CAS: 209410-46-8

Please enquire for more information about Neflamapimod including the price, delivery time and more detailed …

• Formula: C₁₉H₉Cl₂F₂N₃OS
• Purity: Min. 95%
• Molecular weight: 436.26 g/mol