CAS: 209410-46-8 - 5-(2,6-Dichlorophenyl)-2-[(2,4-difluorophenyl)thio]-6H-pyrimido[1,6-b]pyridazin-6-one

Formula: C₁₉H₉Cl₂F₂N₃OS

InChI: InChI=1S/C19H9Cl2F2N3OS/c20-11-2-1-3-12(21)17(11)18-14-5-7-16(25-26(14)9-24-19(18)27)28-15-6-4-10(22)8-13(15)23/h1-9H

InChI key: InChIKey=VEPKQEUBKLEPRA-UHFFFAOYSA-N

SMILES: O=C1N=CN2N=C(SC3=CC=C(F)C=C3F)C=CC2=C1C=4C(Cl)=CC=CC4Cl

Synonyms:

• 5-(2,6-Dichlorophenyl)-2-(2,4-difluorophenyl)sulfanylpyridazino[6,1-f]pyrimidin-6-one
• 5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)sulfanyl]-6H-pyrimido[1,6-b]pyridazin-6-one
• 6H-Pyrimido[1,6-b]pyridazin-6-one, 5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)thio]-
• Neflamapimod
• Vd 31745
• Vrt 031745
• Vx-745
• 5-(2,6-Dichlorophenyl)-2-[(2,4-difluorophenyl)thio]-6H-pyrimido[1,6-b]pyridazin-6-one

6H-Pyrimido[1,6-b]pyridazin-6-one, 5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)thio]-

CAS: 209410-46-8

• Formula: C₁₉H₉Cl₂F₂N₃OS
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 436.2621

VX-745

CAS: 209410-46-8

• Formula: C₁₉H₉Cl₂F₂N₃OS
• Purity: 99.8% (Typical Value in Batch COA)
• Color and Shape: yellow solid
• Molecular weight: 436.26g/mol

VX-745

CAS: 209410-46-8

Neflamapimod

CAS: 209410-46-8

Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity …

• Formula: C₁₉H₉Cl₂F₂N₃OS
• Purity: 99.02% - ≥95%
• Color and Shape: Solid
• Molecular weight: 436.26

5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)thio)-6H-pyrimido[1,6-b]pyridazin-6-one

CAS: 209410-46-8

• Purity: 95.0%
• Molecular weight: 436.260009765625

VX 745

CAS: 209410-46-8

Applications VX 745 is a potent and selective inhibitor of p38α mitogen-activated protein (MAP) kinase. …

• Formula: C₁₉H₉Cl₂F₂N₃OS
• Color and Shape: Neat
• Molecular weight: 436.26

Neflamapimod

CAS: 209410-46-8

5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)thio)-6H-pyrimido[1,6-B]pyridazine-6-one (NVP-BEZ235) is a molecule that inhibits the activity of the phosphoinositide 3 kinase (PI3K) …

• Formula: C₁₉H₉Cl₂F₂N₃OS
• Purity: Min. 95%
• Molecular weight: 436.26 g/mol