CAS 209481-20-9

5-Chloro-N-[4-methoxy-3-(1-piperazinyl)phenyl]-3-methylbenzo[b]thiophene-2-sulfonamide

Description:

5-Chloro-N-[4-methoxy-3-(1-piperazinyl)phenyl]-3-methylbenzo[b]thiophene-2-sulfonamide is a synthetic organic compound characterized by its complex structure, which includes a benzo[b]thiophene core, a sulfonamide functional group, and a piperazine moiety. This compound typically exhibits properties such as moderate solubility in organic solvents and potential bioactivity, making it of interest in medicinal chemistry, particularly in the development of pharmaceuticals. The presence of chlorine and methoxy groups can influence its electronic properties and reactivity, while the piperazine ring may enhance its interaction with biological targets. The sulfonamide group is known for its role in various therapeutic applications, including antibacterial and diuretic effects. Overall, this compound's unique structural features suggest potential applications in drug discovery and development, particularly in targeting specific biological pathways. However, detailed studies on its pharmacokinetics, toxicity, and efficacy would be necessary to fully understand its potential uses in medicine.

Formula: C₂₀H₂₂ClN₃O₃S₂

InChI: InChI=1S/C20H22ClN3O3S2/c1-13-16-11-14(21)3-6-19(16)28-20(13)29(25,26)23-15-4-5-18(27-2)17(12-15)24-9-7-22-8-10-24/h3-6,11-12,22-23H,7-10H2,1-2H3

InChI key: InChIKey=LOCQRDBFWSXQQI-UHFFFAOYSA-N

SMILES: CC=1C=2C(SC1S(NC3=CC(=C(OC)C=C3)N4CCNCC4)(=O)=O)=CC=C(Cl)C2

Synonyms:

• 5-Chloro-N-[4-methoxy-3-(1-piperazinyl)phenyl]-3-methylbenzo[b]thiophene-2-sulfonamide
• Benzo[b]thiophene-2-sulfonamide, 5-chloro-N-[4-methoxy-3-(1-piperazinyl)phenyl]-3-methyl-
• SB 737050
• SB 270146
• SB 271046

SB 271046 hydrochloride

CAS: 209481-20-9

Formula: C₂₀H₂₃Cl₂N₃O₃S₂

Color and Shape: Solid

Molecular weight: 488.4509

Ref: IN-DA002K9A

SB271046 HCl

CAS: 209481-20-9

SB271046 is a ligand that binds to the 5-HT6 receptor. It has been shown to inhibit the activation of hippocampal neurons, which may be due to its ability to activate dopamine receptors. SB271046 also inhibits the binding of glutamate to its receptors and hyperpolarizes hippocampal neurons by inhibiting calcium influx. The drug has been shown to have beneficial effects on locomotor activity in animal models with Parkinson's disease, although it does not show any beneficial effects on Parkinsonian symptoms such as tremor or rigidity.

Formula: C₂₀H₂₂ClN₃O₃S₂

Purity: Min. 95%

Molecular weight: 451.99 g/mol

Ref: 3D-JIA48120