CAS 21256-18-8: Oxaprozin

Description: Oxaprozin is a nonsteroidal anti-inflammatory drug (NSAID) primarily used for the treatment of osteoarthritis and rheumatoid arthritis. It functions by inhibiting the cyclooxygenase (COX) enzymes, which play a crucial role in the synthesis of prostaglandins, thereby reducing inflammation, pain, and fever. Oxaprozin is characterized by its long half-life, allowing for once-daily dosing, which can enhance patient compliance. The chemical structure of oxaprozin includes a propionic acid derivative, and it is classified as a member of the oxicam class of NSAIDs. It is typically administered orally and is well-absorbed in the gastrointestinal tract. Common side effects may include gastrointestinal discomfort, headache, and dizziness, while more serious risks involve cardiovascular and gastrointestinal complications. As with other NSAIDs, caution is advised in patients with pre-existing conditions such as peptic ulcer disease or renal impairment. Overall, oxaprozin is an effective option for managing chronic pain associated with inflammatory conditions.

Formula: C₁₈H₁₅NO₃

InChI: InChI=1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21)

InChI key: InChIKey=OFPXSFXSNFPTHF-UHFFFAOYSA-N

SMILES: O=C(O)CCC1=NC(C=2C=CC=CC2)=C(O1)C=3C=CC=CC3

Synonyms:

• 2-Oxazolepropanoic acid, 4,5-diphenyl-
• 2-Oxazolepropionic acid, 4,5-diphenyl-
• 3-(4,5-Diphenyl-1,3-Oxazol-2-Yl)Propanoic Acid
• 3-(4,5-Diphenyl-1,3-Oxazol-2-Yl)Propionic Acid
• 3-(4,5-Diphenyl-2-Oxazolyl)Propionic Acid
• 3-(4,5-Diphenyloxazol-2-yl)propanoic acid
• 3-(4,5-Diphenyloxazol-2-yl)propionic acid
• 4,5-Diphenyl-2-Oxazolepropanoic Acid
• 4,5-Diphenyl-2-oxazolepropionic acid
• Actirin
• Alvo
• Daypro
• Durapro
• Duraprost
• Nsc 310839
• Oxapro
• Oxaprosin
• Oxaprozina
• Oxaprozine
• Oxoprazine
• Wy 21743
• β-(4,5-Diphenyloxazol-2-yl)propionic acid
• Oxaprozin

Oxaprozin

CAS: 21256-18-8

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

• Formula: C₁₈H₁₅NO₃
• Color and Shape: Powder
• Molecular weight: 293.10519

Oxaprozin

CAS: 21256-18-8

Oxaprozin (Oxaprozinum) is a Nonsteroidal Anti-inflammatory Drug.

• Formula: C₁₈H₁₅NO₃
• Purity: 99.02%
• Color and Shape: Solid
• Molecular weight: 293.32

3-(4,5-Diphenyloxazol-2-yl)propanoic acid

CAS: 21256-18-8

• Formula: C₁₈H₁₅NO₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 293.3166

Oxaprozin-d5

CAS: 21256-18-8

• Formula: C₁₈H₁₀D₅NO₃
• Color and Shape: White To Off-White Solid
• Molecular weight: 298.35

Oxaprozine

CAS: 21256-18-8

• Formula: C₁₈H₁₅NO₃
• Molecular weight: 293.32

Oxaprozin

CAS: 21256-18-8

• Formula: C₁₈H₁₅NO₃
• Color and Shape: White To Off-White Solid
• Molecular weight: 293.33

Oxaprozin

CAS: 21256-18-8

• Formula: C₁₈H₁₅NO₃
• Color and Shape: Neat
• Molecular weight: 293.32

Oxaprozin

CAS: 21256-18-8

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₈H₁₅NO₃
• Color and Shape: White to light beige, Crystalline powder
• Molecular weight: 293.32

Oxaprozin

CAS: 21256-18-8

• Formula: C₁₈H₁₅NO₃
• Color and Shape: Neat
• Molecular weight: 293.32

Oxaprozin

CAS: 21256-18-8

• Formula: C₁₈H₁₅NO₃
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 293.32

3-(4,5-Diphenyl-1,3-oxazol-2-yl)propanoic acid

CAS: 21256-18-8

• Formula: C₁₈H₁₅NO₃
• Purity: 98%
• Color and Shape: off-white solid
• Molecular weight: 293.32g/mol

Oxaprozin-d10

CAS: 21256-18-8

Applications Oxaprozin-d10 is the labeled analogue of Oxaprozin (O845400), an anti-inflammatory drug. Oxaprozin was comparable …

• Formula: C₁₈H₅D₁₀NO₃
• Color and Shape: Neat
• Molecular weight: 303.38

3-(4,5-Diphenyl-1,3-oxazol-2-yl)propanoic acid

CAS: 21256-18-8

• Purity: 97.0%
• Color and Shape: Solid
• Molecular weight: 293.3219909667969

Oxaprozin

CAS: 21256-18-8

Applications Oxaprozin is an anti-inflammatory drug. Oxaprozin was comparable to Aspirin (A687780). References Whitehouse, M.W., …

• Formula: C₁₈H₁₅NO₃
• Color and Shape: Neat
• Molecular weight: 293.32

Oxaprozin

CAS: 21256-18-8

COX1/2 inhibitor; inhibitor of Akt activation

• Formula: C₁₈H₁₅NO₃
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 293.32 g/mol

Oxaprozin - Bio-X ™

CAS: 21256-18-8

Oxaprozin is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis and rheumatoid …

• Formula: C₁₈H₁₅NO₃
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 293.32 g/mol