CAS 21256-18-8

Oxaprozin

Description:

Oxaprozin is a nonsteroidal anti-inflammatory drug (NSAID) primarily used for the treatment of osteoarthritis and rheumatoid arthritis. It functions by inhibiting the cyclooxygenase (COX) enzymes, which play a crucial role in the synthesis of prostaglandins, thereby reducing inflammation, pain, and fever. Oxaprozin is characterized by its long half-life, allowing for once-daily dosing, which can enhance patient compliance. The chemical structure of oxaprozin includes a propionic acid derivative, and it is classified as a member of the oxicam class of NSAIDs. It is typically administered orally and is well-absorbed in the gastrointestinal tract. Common side effects may include gastrointestinal discomfort, headache, and dizziness, while more serious risks involve cardiovascular and gastrointestinal complications. As with other NSAIDs, caution is advised in patients with pre-existing conditions such as peptic ulcer disease or renal impairment. Overall, oxaprozin is an effective option for managing chronic pain associated with inflammatory conditions.

Formula: C₁₈H₁₅NO₃

InChI: InChI=1/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21)

InChI key: InChIKey=OFPXSFXSNFPTHF-UHFFFAOYSA-N

SMILES: C(CC(O)=O)C1=NC(=C(O1)C2=CC=CC=C2)C3=CC=CC=C3

Synonyms:

• 2-Oxazolepropanoic acid, 4,5-diphenyl-
• 2-Oxazolepropionic acid, 4,5-diphenyl-
• 3-(4,5-Diphenyl-1,3-Oxazol-2-Yl)Propanoic Acid
• 3-(4,5-Diphenyl-1,3-Oxazol-2-Yl)Propionic Acid
• 3-(4,5-Diphenyl-2-Oxazolyl)Propionic Acid
• 3-(4,5-Diphenyloxazol-2-yl)propanoic acid
• 3-(4,5-Diphenyloxazol-2-yl)propionic acid
• 4,5-Diphenyl-2-Oxazolepropanoic Acid
• 4,5-Diphenyl-2-oxazolepropionic acid
• Actirin
• Alvo
• Daypro
• Durapro
• Duraprost
• Nsc 310839
• Oxapro
• Oxaprosin
• Oxaprozina
• Oxaprozine
• Oxoprazine
• Wy 21743
• β-(4,5-Diphenyloxazol-2-yl)propionic acid
• Oxaprozin
• 4,5-diphenyl-2-oxazolepropionicaci
• Dxaprozin
• 3-(4,5-Diphenyl-2-oxazoyl)propionic acid
• 4,5-Diphenyloxazole-2-propionic acid
• 4,5-Diphenyl-2-oxazolepropanoic acid, Daypro
• 4,5-diphenyl-2-oxazolepropionicacid
• 4,5-diphenyl-2-oxazolepropanoicaci

Oxaprozin

CAS: 21256-18-8

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₁₈H₁₅NO₃

Color and Shape: Powder

Molecular weight: 293.10519

Ref: 45-1482207

Oxaprozin

CAS: 21256-18-8

Oxaprozin (Oxaprozinum) is a Nonsteroidal Anti-inflammatory Drug.

Formula: C₁₈H₁₅NO₃

Purity: 98.53%

Color and Shape: White Solid

Molecular weight: 293.32

Ref: TM-T0708

3-(diphenyl-1,3-oxazol-2-yl)propanoic acid

CAS: 21256-18-8

Formula: C₁₈H₁₅NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 293.3166

Ref: IN-DA003I2X

3-(4,5-Diphenyl-1,3-oxazol-2-yl)propanoic acid

CAS: 21256-18-8

3-(4,5-Diphenyl-1,3-oxazol-2-yl)propanoic acid

Formula: C₁₈H₁₅NO₃

Purity: 98%

Color and Shape: Beige Solid

Molecular weight: 293.3166

Ref: 54-OR8088

Oxaprozine

CAS: 21256-18-8

Formula: C₁₈H₁₅NO₃

Molecular weight: 293.32

Ref: 7W-GP7057

Oxaprozin

CAS: 21256-18-8

Formula: C₁₈H₁₅NO₃

Color and Shape: White To Off-White Solid

Molecular weight: 293.33

Ref: 4Z-O-044001

Oxaprozin

CAS: 21256-18-8

Oxaprozin

Formula: C₁₈H₁₅NO₃

Purity: ≥98%

Molecular weight: 293.32

Ref: 54-BUP14159

Oxaprozin-d5

CAS: 21256-18-8

Formula: C₁₈H₁₀D₅NO₃

Color and Shape: White To Off-White Solid

Molecular weight: 298.35

Ref: 4Z-O-044002

Oxaprozin

Controlled Product

CAS: 21256-18-8

Formula: C₁₈H₁₅NO₃

Color and Shape: Neat

Molecular weight: 293.32

Ref: 86-MM3654.00

Oxaprozin

CAS: 21256-18-8

Formula: C₁₈H₁₅NO₃

Color and Shape: Neat

Molecular weight: 293.32

Ref: 04-C15727800

Oxaprozin

CAS: 21256-18-8

Formula: C₁₈H₁₅NO₃

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 293.32

Ref: 3B-O0377

Oxaprozin

Controlled Product

CAS: 21256-18-8

Applications Oxaprozin is an anti-inflammatory drug. Oxaprozin was comparable to Aspirin (A687780).
References Whitehouse, M.W., et al.: Biochem. Pharmacol., 20, 2309 (1971), Janssen, F.W., et al.: Drug Metab. Dispos., 6, 465 (1978), Shriver, D.A., et al.: Toxicol. Appl. Pharmacol., 42, 75 (1977),

Formula: C₁₈H₁₅NO₃

Color and Shape: Neat

Molecular weight: 293.32

Ref: TR-O845400

Oxaprozin-d10

Controlled Product

CAS: 21256-18-8

Applications Oxaprozin-d10 is the labeled analogue of Oxaprozin (O845400), an anti-inflammatory drug. Oxaprozin was comparable to Aspirin (A687780).
References Whitehouse, M.W., et al.: Biochem. Pharmacol., 20, 2309 (1971); Janssen, F.W., et al.: Drug Metab. Dispos., 6, 465 (1978); Shriver, D.A., et al.: Toxicol. Appl. Pharmacol., 42, 75 (1977)

Formula: C₁₈H₅D₁₀NO₃

Color and Shape: Neat

Molecular weight: 303.38

Ref: TR-O845402

3-(4,5-Diphenyl-1,3-oxazol-2-yl)propanoic acid

CAS: 21256-18-8

Purity: 97.0%

Color and Shape: Solid

Molecular weight: 293.3219909667969

Ref: 10-F066202

Oxaprozin - Bio-X ™

CAS: 21256-18-8

Oxaprozin is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis and rheumatoid arthritis. This drug relieves swelling and inflammation by inhibiting the enzyme cyclooxygenase which in turn inhibits prostaglandin synthesis.

Formula: C₁₈H₁₅NO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 293.32 g/mol

Ref: 3D-BO164184

Oxaprozin

CAS: 21256-18-8

COX1/2 inhibitor; inhibitor of Akt activation

Formula: C₁₈H₁₅NO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 293.32 g/mol

Ref: 3D-FO26614

Oxaprozin

CAS: 21256-18-8

Formula: C₁₈H₁₅NO₃

Molecular weight: 293.32

Ref: ST-EA-CP-O40000

Oxaprozin

CAS: 21256-18-8

3-(4,5-Diphenyloxazol-2-yl)propanoic acid

Formula: C₁₈H₁₅NO₃

Purity: 99%

Molecular weight: 293.32

Ref: IN-DG19346