CAS 2137047-43-7

Formula: C16H12F5N3O

InChI: InChI=1S/C16H12F5N3O/c1-7-6-11(16(19,20)21)24-15(22-7)12(8(2)23-24)9-4-5-10(25-3)14(18)13(9)17/h4-6H,1-3H3

InChI key: NYBZCKAQIIPSDS-UHFFFAOYSA-N

SMILES: CC1=NC2=C(C(=NN2C(=C1)C(F)(F)F)C)C3=C(C(=C(C=C3)OC)F)F

VU6005649

CAS: 2137047-43-7

VU6005649

Formula: C₁₆H₁₂F₅N₃O

Purity: 99.5%

Molecular weight: 357.28

Ref: 54-BUP10314

VU 6005649

CAS: 2137047-43-7

Formula: C₁₆H₁₂F₅N₃O

Purity: 98%

Color and Shape: Solid

Molecular weight: 357.2780

Ref: IN-DA01EOM9

VU6005649

CAS: 2137047-43-7

VU6005649 is an agonist of CNS penetrant mGlu7/8 receptor (EC50s: 0.65 μM and 2.6 μM for mGlu7 receptor and mGlu8 receptor, respectively).

Formula: C₁₆H₁₂F₅N₃O

Purity: 99.87%

Color and Shape: Yellow Solid

Molecular weight: 357.278

Ref: TM-T13321

VU 6005649

CAS: 2137047-43-7

VU 6005649 is a toolbox compound that modulates the activity of glutamate receptors in the brain. It has been shown to be an agonist at metabotropic glutamate receptor 7 (mGluR7) with high selectivity for this subtype. VU 6005649 has been shown to have potent and selective effects on neuronal function, and penetrates the blood-brain barrier. It also shows no binding affinity to other glutamate receptor subtypes, such as mGluR1 and mGluR2/3.

Formula: C₁₆H₁₂F₅N₃O

Purity: Min. 95%

Molecular weight: 357.28 g/mol

Ref: 3D-MKD04743