CAS 2140-71-8: 2′-O-Methylguanosine

Description: 2′-O-Methylguanosine is a modified nucleoside that plays a significant role in various biological processes, particularly in RNA metabolism. It consists of a guanine base attached to a ribose sugar, which is further methylated at the 2′ hydroxyl group. This modification is commonly found in tRNA and rRNA, contributing to the stability and functionality of these molecules. The presence of the methyl group enhances the structural integrity of RNA, influencing its folding and interaction with proteins. 2′-O-Methylguanosine is also involved in the regulation of gene expression and can affect the splicing and translation of RNA. Its chemical formula reflects the presence of carbon, hydrogen, nitrogen, and oxygen atoms, characteristic of nucleosides. The compound is soluble in water and exhibits properties typical of nucleosides, such as forming hydrogen bonds and participating in base pairing. Due to its biological significance, 2′-O-Methylguanosine is of interest in research related to RNA biology, therapeutics, and the development of RNA-based drugs.

Formula: C₁₁H₁₅N₅O₅

InChI: InChI=1S/C11H15N5O5/c1-20-7-6(18)4(2-17)21-10(7)16-3-13-5-8(16)14-11(12)15-9(5)19/h3-4,6-7,10,17-18H,2H2,1H3,(H3,12,14,15,19)/t4-,6-,7-,10-/m1/s1

InChI key: InChIKey=OVYNGSFVYRPRCG-KQYNXXCUSA-N

SMILES: O=C1N=C(N)NC2=C1N=CN2C3OC(CO)C(O)C3OC

Synonyms:

• 1-Methylguanosine = 2-O-Methylguanosine
• Guanosine, 2′-O-methyl-
• 2′-O-Methylguanosine

2'-O-Methylguanosine

CAS: 2140-71-8

• Formula: C₁₁H₁₅N₅O₅
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 297.27

2'-O-Methylguanosine, 99%

CAS: 2140-71-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. …

• Formula: C₁₁H₁₅N₅O₅
• Purity: 99%
• Molecular weight: 297.27

2140-71-8

CAS: 2140-71-8

• Formula: C₁₁H₁₅N₅O₅
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 297.2673

2''-O-Methyl guanosine

CAS: 2140-71-8

• Formula: C₁₁H₁₅N₅O₅
• Purity: ≥ 98.0%
• Color and Shape: White to almost white powder or crystals
• Molecular weight: 297.27

2-Amino-9-((2R,3R,4R,5R)-4-Hydroxy-5-(Hydroxymethyl)-3-Methoxytetrahydrofuran-2-Yl)-1H-Purin-6(9H)-One

CAS: 2140-71-8

• Purity: 98%
• Molecular weight: 297.27g/mol

2'-O-Methylguanosine

CAS: 2140-71-8

• Purity: 95.0%
• Color and Shape: Solid, White to almost white powder
• Molecular weight: 297.27099609375

2'-O-Methylguanosine

CAS: 2140-71-8

• Formula: C₁₁H₁₅N₅O₅
• Molecular weight: 297.27

2'-OMe-Guanosine

CAS: 2140-71-8

2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a …

• Formula: C₁₁H₁₅N₅O₅
• Purity: 98.92%
• Color and Shape: White Solid
• Molecular weight: 297.27

2'-O-Methyl Guanosine-d3

CAS: 2140-71-8

Applications 2'-O-Methyl Guanosine-d3 is a labeled analogue of 2'-O-Methyl Guanosine (M311825), which is a Guanosine …

• Formula: C₁₁D₃H₁₂N₅O₅
• Color and Shape: Neat
• Molecular weight: 300.29

2'-O-Methyl Guanosine

CAS: 2140-71-8

Applications Guanosine analog. Used for preparation of nucleoside derivatives as inhibitors of RNA-dependent RNA viral …

• Formula: C₁₁H₁₅N₅O₅
• Color and Shape: Neat
• Molecular weight: 297.27

2'-O-Methylguanosine

CAS: 2140-71-8

2'-O-Methylguanosine is a nucleoside that contains a 2'-O-methyl group at the 2' position of the …

• Formula: C₁₁H₁₅N₅O₅
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 297.27 g/mol