CAS 2140301-96-6

Brepocitinib P-Tosylate

CAS: 2140301-96-6

Brepocitinib P-Tosylate (PF-06700841 P-Tosylate) is a potent dual inhibitor of Janus kinase 1 (JAK1) and TYK2 (IC50s of 17 nM and 23 nM, respectively).

Formula: C₂₅H₂₉F₂N₇O₄S

Purity: 99.82% - 99.97%

Color and Shape: Solid

Molecular weight: 561.6

Ref: TM-T12427

Brepocitinib P-Tosylate

CAS: 2140301-96-6

Brepocitinib P-Tosylate

Purity: ≥98%

Molecular weight: 561.6g/mol

Ref: 54-BUP08558

Pf-06700841 (p-tosylate)

CAS: 2140301-96-6

Pf-06700841 is a peptide that can be used as a research tool for the study of ion channels and protein interactions. It is an inhibitor of the potassium channel, which is involved in the regulation of neuronal excitability. Pf-06700841 also blocks L-type calcium channels, which are important in cell proliferation and differentiation. Pf-06700841 has been shown to inhibit receptor binding at low concentrations, with increased potency at higher concentrations. At high concentrations, it acts as a ligand to activate G protein coupled receptors. Pf-06700841 has been shown to reduce pain in animal models by blocking pain receptors as well as inhibiting the release of inflammatory cytokines from immune cells.

Formula: C₂₅H₂₉F₂N₇O₄S

Purity: Min. 95%

Molecular weight: 561.6 g/mol

Ref: 3D-QKD30196