CAS 2140301-96-6

Formula: C25H29F2N7O4S

InChI: InChI=1S/C18H21F2N7O.C7H8O3S/c1-25-8-11(7-22-25)23-17-21-5-4-15(24-17)26-9-12-2-3-13(10-26)27(12)16(28)14-6-18(14,19)20;1-6-2-4-7(5-3-6)11(8,9)10/h4-5,7-8,12-14H,2-3,6,9-10H2,1H3,(H,21,23,24);2-5H,1H3,(H,8,9,10)/t12-,13+,14-;/m0./s1

InChI key: FAKGOYNHHHOTEN-VDTKTRGNSA-N

SMILES: CC1=CC=C(C=C1)S(=O)(=O)O.CN1C=C(C=N1)NC2=NC=CC(=N2)N3C[C@H]4CC[C@@H](C3)N4C(=O)[C@@H]5CC5(F)F

Brepocitinib P-Tosylate

CAS: 2140301-96-6

Brepocitinib P-Tosylate (PF-06700841 P-Tosylate) is a potent dual inhibitor of Janus kinase 1 (JAK1) and TYK2 (IC50s of 17 nM and 23 nM, respectively).

Formula: C₂₅H₂₉F₂N₇O₄S

Purity: 99.82% - 99.97%

Color and Shape: Solid

Molecular weight: 561.604

Ref: TM-T12427

Brepocitinib P-Tosylate

CAS: 2140301-96-6

Brepocitinib P-Tosylate

Formula: C₂₅H₂₉F₂N₇O₄S

Purity: ≥98%

Molecular weight: 561.6

Ref: 54-BUP08558

Pf-06700841 (p-tosylate)

CAS: 2140301-96-6

Pf-06700841 is a peptide that can be used as a research tool for the study of ion channels and protein interactions. It is an inhibitor of the potassium channel, which is involved in the regulation of neuronal excitability. Pf-06700841 also blocks L-type calcium channels, which are important in cell proliferation and differentiation. Pf-06700841 has been shown to inhibit receptor binding at low concentrations, with increased potency at higher concentrations. At high concentrations, it acts as a ligand to activate G protein coupled receptors. Pf-06700841 has been shown to reduce pain in animal models by blocking pain receptors as well as inhibiting the release of inflammatory cytokines from immune cells.

Formula: C₂₅H₂₉F₂N₇O₄S

Purity: Min. 95%

Molecular weight: 561.6 g/mol

Ref: 3D-QKD30196